Density functional theory study of interaction of graphene with hypoxanthine, xanthine, and uric acid

被引:19
|
作者
Yang, Junwei [1 ]
Yuan, Yanhong [1 ]
Hua, Zhao [1 ]
机构
[1] Shanghai Dianji Univ, Dept Math & Phys, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
Graphene; density functional theory; interaction; SENSITIVE ELECTROCHEMICAL SENSOR; GLASSY-CARBON ELECTRODE; PURINE; COMPOSITE; VOLTAMMETRY; NUCLEOBASES; CAFFEINE; DISEASE; URATE;
D O I
10.1080/00268976.2016.1189009
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Hypoxanthine (HX), xanthine (XA), and uric acid (UA) are important molecules in human beings. However, the physics underlying the interaction between these molecules and carbon nanomaterials is still unclear. In this study, we theoretically anlaysed the interaction of the graphene with HX, XA, and UA via the LDA, Perdew-Burke-Ernzerhof, and a second version of van der Waals (vdW)-DF2 exchange-correlation functionals of density functional theory. It was observed that these molecules could be adsorbed on the surface of the graphene steadily. The adsorption energies of these molecules on the graphene for the same site in vdW-DF2 functional show the following ordering: UA > XA > HX, the adsorption distances the following ordering: UA < XA < HX. The mechanism of this stable adsorption was revealed to be pi-pi and O-pi interactions between these molecules and the graphene. Simulated scanning tunnelling microscopy (STM) images of HX, XA, and UA on the surface of the graphene layer as application, HX can be distinguished from XA and UA via the STM technique as a result of the interaction between the graphene and these molecules. The findings of this study provide a theoretical reference in the development and design of highly accurate biodevices and biosensors. [GRAPHICS] .
引用
收藏
页码:2157 / 2163
页数:7
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