An Efficient One-Pot Solvent-Free Synthesis of 2,3-Dihydroquinazoline-4(1H)-ones via Al/Al2O3 Nanoparticles

被引：39

作者：

Kassaee, M. Z. ^{[1
]}

Rostamizadeh, Shahnaz ^{[2
]}

Shadjou, Nasrin ^{[2
]}

Motamedi, Elahe ^{[1
]}

Esmaeelzadeh, Maryam ^{[2
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

[2] KN Toosi Univ Technol, Dept Chem, Tehran, Iran

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2010年 / 47卷 / 06期

关键词：

DERIVATIVES; PARTICLES; IODINE;

D O I：

10.1002/jhet.506

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient one-pot, solvent-free method is reported for the synthesis of 2-pheny1-2,3-dihydroquinazoline-4(1H)-one as well as its o-Cl, o-OMe, m-Br, m-NO2, p-OH, p-NO2, p-CN, p-PhCH2O, p-Cl, p-F, p-Br, p-Me, and o,m-dichloro derivatives, using our "as-prepared" arc discharge fabricated Al/Al2O3 nanoparticles. Compared with our previous report and other known methods, this route gives higher yields with shorter reaction times, whereas its green catalyst appears recyclable at least four times-with minor decrease in its catalytic activity, under mild conditions.

引用

页码：1421 / 1424

页数：4

共 25 条

[1] A novel method for the synthesis of 4(3H)-quinazolinones [J].