Coronary artery aneurysms in children is not always Kawasaki disease: a case report on Takayasu arteritis

被引:4
|
作者
Lee, Michelle [1 ,2 ]
Meidan, Esra [1 ,3 ]
Son, MaryBeth [1 ,3 ]
Dionne, Audrey [2 ,3 ]
Newburger, Jane W. [2 ,3 ]
Friedman, Kevin G. [2 ,3 ]
机构
[1] Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
[2] Boston Childrens Hosp, Dept Cardiol, 300 Longwood Avenue,Farley 2, Boston, MA 02115 USA
[3] Boston Childrens Hosp, Div Immunol, Boston, MA USA
关键词
Kawasaki disease; Takayasu's arteritis; Coronary artery aneurysm; Case report; MYOCARDIAL-INFARCTION; POLYARTERITIS-NODOSA; INVOLVEMENT; GRANULOMATOSIS; PATIENT;
D O I
10.1186/s41927-021-00197-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Coronary artery (CA) aneurysms in children are a rare but potentially life-threatening finding and are highly associated with Kawasaki disease (KD). Case presentation We describe a four-year-old female with a vasculitis and CA aneurysms. She had a prolonged course with recurrent fever and systemic inflammation several times upon discontinuation of steroid treatment. Due in part to the CA aneurysms, she initially was diagnosed with KD but due to the unusual clinical course, further evaluation was performed. Abdominal and chest MRI/A revealed diffuse aortitis suggestive of a large vessel vasculitis, specifically Takayasu arteritis. With treatment targeted for Takayasu arteritis, there was resolution of fever and inflammation and the CA aneurysms improved. Conclusions This case demonstrates the utility in broadening the differential diagnosis in cases of presumed KD with CA involvement in which the clinical course is atypical for KD.
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页数:6
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