SOD1 aggregates in ALS: Cause, correlate or consequence?

被引：54
|
作者：
Brown, RH [1 ]
机构：
[1] Massachusetts Gen Hosp, Day Neuromuscular Res Lab, Charlestown, MA 02129 USA
来源：
NATURE MEDICINE | 1998年 / 4卷 / 12期
关键词：
D O I：
10.1038/3945
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Increased expression of wild-type SOD1 in mice with ALS does not slow disease progression or diminish the pathological changes in motor neurons.
引用
收藏
页码：1362 / 1364
页数：3
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