Cerebrospinal fluid-based diagnostics of CT-negative subarachnoid haemorrhage

被引:11
作者
Tumani, H. [1 ]
Petzold, A. [1 ]
Wick, M. [1 ]
Kuehn, H.-J. [1 ]
Uhr, M. [1 ]
Otto, M. [1 ]
Regeniter, A. [1 ]
Brettschneider, J. [1 ]
机构
[1] Univ Ulm, Abt Neurol, D-89081 Ulm, Germany
来源
NERVENARZT | 2010年 / 81卷 / 08期
关键词
Subarachnoid haemorrhage; Cerebrospinal fluid; Xanthochromia; Cytology; Ferritin; Spectrophotometry; TRAUMATIC LUMBAR PUNCTURE; COMPUTED-TOMOGRAPHY; SPECTROPHOTOMETRY; XANTHOCHROMIA; HEADACHE; FERRITIN; STILL; DIFFERENTIATION; FREQUENCY; BILIRUBIN;
D O I
10.1007/s00115-010-2997-5
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The diagnostic investigation of CT-negative subarachnoid haemorrhage (SAH) is a particular challenge in clinical neurology. Cerebrospinal fluid (CSF) analysis via lumbar puncture is the method of choice. The diagnosis of SAH in CSF is based on a bloody or xanthochromic discoloration of the CSF as well as on findings in non-automated CSF cytology including the detection of erythrophages and siderophages. The automated determination of CSF ferritin concentrations or spectrophotometric detection of xanthochromia may contribute to the diagnosis but are only useful with regard to the overall clinical picture. Generally, the knowledge of the time flow of CSF changes associated with SAH is essential for a correct interpretation of CSF findings.
引用
收藏
页码:973 / 979
页数:7
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