Musculoskeletal Pain Associated With Corticosteroid Therapy in Cancer

被引:17
作者
Frieze, Deborah A. [1 ]
机构
[1] Univ Washington, Med Ctr, Seattle, WA 98195 USA
关键词
Musculoskeletal pain; Corticosteroid therapy; Cancer; Osteoporosis; Osteonecrosis; Myopathy; Myalgia; AVASCULAR NECROSIS; STEROID MYOPATHY; INTENSIVE CHEMOTHERAPY; SOLID TUMORS; OSTEONECROSIS; BONE; DEXAMETHASONE; COMPLICATION; REGIMENS; CHILDREN;
D O I
10.1007/s11916-010-0120-z
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Corticosteroids have multiple uses in the care of the cancer patient. Although they confer benefit to the patient, high doses and extended duration of use may lead to significant adverse effects. Adverse effects such as osteoporosis-induced fractures, osteonecrosis, myopathy and myalgias can cause significant pain and have a negative impact on the patient's quality of life. In this paper, I will review the mechanisms involved in the toxicity, risk factors, prevalence, prevention, and treatment strategies.
引用
收藏
页码:256 / 260
页数:5
相关论文
共 33 条
  • [11] A UK Consensus Group on management of glucocorticoid-induced osteoporosis: an update
    Eastell, R
    Reid, DM
    Compston, J
    Cooper, C
    Fogelman, I
    Francis, RM
    Hosking, DJ
    Purdie, DW
    Ralston, SH
    Reeve, J
    Russell, RGG
    Stevenson, JC
    Torgerson, DJ
    [J]. JOURNAL OF INTERNAL MEDICINE, 1998, 244 (04) : 271 - 292
  • [12] Corticosteroid-induced adverse events in adults - Frequency, screening and prevention
    Fardet, Laurence
    Kassar, Abdulrhaman
    Cabane, Jean
    Flahault, Antoine
    [J]. DRUG SAFETY, 2007, 30 (10) : 861 - 881
  • [13] COMPARISON OF A STANDARD REGIMEN (CHOP) WITH 3 INTENSIVE CHEMOTHERAPY REGIMENS FOR ADVANCED NON-HODGKINS-LYMPHOMA
    FISHER, RI
    GAYNOR, ER
    DAHLBERG, S
    OKEN, MM
    GROGAN, TM
    MIZE, EM
    GLICK, JH
    COLTMAN, CA
    MILLER, TP
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (14) : 1002 - 1006
  • [14] THE UNTOWARD EFFECTS OF STEROID TREATMENT ON THE MUSCULOSKELETAL SYSTEM AND WHAT TO DO ABOUT THEM
    HOLLISTER, JR
    [J]. JOURNAL OF ASTHMA, 1992, 29 (06) : 363 - 368
  • [15] Homik J, 2000, COCHRANE DB SYST REV
  • [16] LESSER GJ, 1997, P AM SOC CLIN ONC
  • [17] LIM SS, CORTICOSTEROID INDUC
  • [18] New developments in the pathogenesis and treatment of steroid-induced osteoporosis
    Manolagas, SC
    Weinstein, RS
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 1999, 14 (07) : 1061 - 1066
  • [19] Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: A report from the children's cancer group
    Mattano, LA
    Sather, HN
    Trigg, ME
    Nachman, JB
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (18) : 3262 - 3272
  • [20] OBRIEN TJ, 1992, CLIN ORTHOP RELAT R, P176