Asymmetric palladium-catalyzed benzylic nucleophilic substitution:: high enantioselectivity with the DUPHOS family ligands

被引：29

作者：

Assié, M ^{[1
]}

Legros, JY ^{[1
]}

Fiaud, JC ^{[1
]}

机构：

[1] Univ Paris 11, Inst Chim Mol & Mat Orsay, CNRS, UMR 8075,Lab Catalyse Mol, F-91405 Orsay, France

来源：

TETRAHEDRON-ASYMMETRY | 2005年 / 16卷 / 06期

关键词：

D O I：

10.1016/j.tetasy.2005.01.032

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The asymmetric palladium-catalyzed benzylic reaction of 1-(2-naphthyl)ethyl acetate and its 6-methoxy substituted analogue with dimethyl malonate anion led to substitution products with up to 90% ee when the iPr-DUPHOS chiral ligand was used. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1183 / 1187

页数：5

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