Graphene in biomedicine: opportunities and challenges

被引:82
作者
Feng, Liangzhu [1 ]
Liu, Zhuang [1 ]
机构
[1] Soochow Univ, Jiangsu Key Lab Carbon Based Funct Mat & Devices, Inst Funct Nano & Soft Mat, Suzhou 215123, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
biosensing; cancer therapy; drug delivery; graphene; toxicology; RESONANCE ENERGY-TRANSFER; CARBON NANOTUBES; EPITAXIAL GRAPHENE; MOLECULAR BEACON; OXIDE; DNA; PLATFORM; ELECTROCHEMILUMINESCENCE; TRANSISTORS; SENSITIVITY;
D O I
10.2217/NNM.10.158
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Graphene, whose discovery won the 2010 Nobel Prize in physics, has been a shining star in the material science in the past few years. Owing to its interesting electrical, optical, mechanical and chemical properties, graphene has found potential applications in a wide range of areas, including biomedicine. In this article, we will summarize the latest progress of using graphene for various biomedical applications, including drug delivery, cancer therapies and biosensing, and discuss the opportunities and challenges in this emerging field.
引用
收藏
页码:317 / 324
页数:8
相关论文
共 80 条
[1]   Solution-Gated Epitaxial Graphene as pH Sensor [J].
Ang, Priscilla Kailian ;
Chen, Wei ;
Wee, Andrew Thye Shen ;
Loh, Kian Ping .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (44) :14392-+
[2]   Metal decorated graphene nanosheets as immobilization matrix for amperometric glucose biosensor [J].
Baby, Tessy Theres ;
Aravind, S. S. Jyothirmayee ;
Arockiadoss, T. ;
Rakhi, R. B. ;
Ramaprabhu, S. .
SENSORS AND ACTUATORS B-CHEMICAL, 2010, 145 (01) :71-77
[3]   A Graphene Oxide-Organic Dye Ionic Complex with DNA-Sensing and Optical-Limiting Properties [J].
Balapanuru, Janardhan ;
Yang, Jia-Xiang ;
Xiao, Si ;
Bao, Qiaoliang ;
Jahan, Maryam ;
Polavarapu, Lakshminarayana ;
Wei, Ji ;
Xu, Qing-Hua ;
Loh, Kian Ping .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (37) :6549-6553
[4]   Graphene Fluorescence Resonance Energy Transfer Aptasensor for the Thrombin Detection [J].
Chang, Haixin ;
Tang, Longhua ;
Wang, Ying ;
Jiang, Jianhui ;
Li, Jinghong .
ANALYTICAL CHEMISTRY, 2010, 82 (06) :2341-2346
[5]   Graphene-based materials in electrochemistry [J].
Chen, Da ;
Tang, Longhua ;
Li, Jinghong .
CHEMICAL SOCIETY REVIEWS, 2010, 39 (08) :3157-3180
[6]   Mechanically strong, electrically conductive, and biocompatible graphene paper [J].
Chen, Haiqun ;
Mueller, Marc B. ;
Gilmore, Kerry J. ;
Wallace, Gordon G. ;
Li, Dan .
ADVANCED MATERIALS, 2008, 20 (18) :3557-+
[7]   Electrochemiluminescence Biosensor for Glucose Based on Graphene/Nafion/GOD Film Modified Glassy Carbon Electrode [J].
Chen, Xiaoping ;
Ye, Huazhen ;
Wang, Wanzong ;
Qui, Bin ;
Lin, Zhenyu ;
Chen, Guonan .
ELECTROANALYSIS, 2010, 22 (20) :2347-2352
[8]   Graphene and Nanowire Transistors for Cellular Interfaces and Electrical Recording [J].
Cohen-Karni, Tzahi ;
Qing, Quan ;
Li, Qiang ;
Fang, Ying ;
Lieber, Charles M. .
NANO LETTERS, 2010, 10 (03) :1098-1102
[9]   Fluorescence Resonance Energy Transfer between Quantum Dots and Graphene Oxide for Sensing Biomolecules [J].
Dong, Haifeng ;
Gao, Wenchao ;
Yan, Feng ;
Ji, Hanxu ;
Ju, Huangxian .
ANALYTICAL CHEMISTRY, 2010, 82 (13) :5511-5517
[10]   Electrical Detection of DNA Hybridization with Single-Base Specificity Using Transistors Based on CVD-Grown Graphene Sheets [J].
Dong, Xiaochen ;
Shi, Yumeng ;
Huang, Wei ;
Chen, Peng ;
Li, Lain-Jong .
ADVANCED MATERIALS, 2010, 22 (14) :1649-+