Painful ophthalmoplegia in a patient with a history of marginal zone lymphoma

被引:0
作者
Van Bogaert, C. [1 ]
Mathey, C. [1 ]
Vierasu, I [1 ]
Trotta, N. [1 ]
Rocq, L. [2 ]
Wolfromm, A. [3 ]
De Wilde, V [3 ]
Goldman, S. [1 ]
机构
[1] CUB Hop Erasme, Dept Nucl Med, Anderlecht, Belgium
[2] CUB Hop Erasme, Dept Anatomopatholgy, Anderlecht, Belgium
[3] CUB Hop Erasme, Dept Haematol, Anderlecht, Belgium
来源
EUROPEAN JOURNAL OF HYBRID IMAGING | 2021年 / 5卷 / 01期
关键词
Painful ophthalmoplegia; Lymphoma; Tolosa Hunt syndrome; IGG4-RELATED DISEASE; ASSOCIATION;
D O I
10.1186/s41824-021-00113-2
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A 73-year-old man with a history of marginal zone lymphoma was admitted to the emergency room for diplopia and ipsilateral headache. The Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) demonstrated intense and symmetrical hypermetabolism of the cavernous sinuses, and hypermetabolic lesions diffusely in the lymph nodes and bones. The diagnosis of high-grade relapse of lymphomatous disease was made. In this context, the homogenous and symmetric lesion of the cavernous sinuses, without any other encephalic or meningeal lesions, raised the hypothesis of a paraneoplastic origin. A plausible paraneoplastic link between the neuro-ophthalmological lesion and the malignant disorder is IgG4-related disease, a condition that may be associated with lymphoma. As in our case, this diagnosis is often presumptive because histopathological confirmation is difficult to obtain.
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页数:7
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