A scoping review protocol on in vivo human plastic exposure and health impacts

被引:5
作者
Goodes, Louise M. [1 ,2 ]
Wong, Enoch V. S. [1 ]
Alex, Jennifer [1 ]
Mofflin, Louise [1 ]
Toshniwal, Priyanka [1 ]
Brunner, Manuel [1 ,3 ]
Solomons, Terena [4 ]
White, Emily [1 ]
Choudhury, Omrik [1 ]
Seewoo, Bhedita J. [1 ,2 ]
Mulders, Yannick R. [1 ]
Dale, Tristan [1 ,5 ,6 ]
Newman, Hamish J. [1 ,7 ,8 ]
Naveed, Alina [1 ]
Lowe, Andrew B. [9 ]
Hendrie, Delia, V [10 ]
Symeonides, Christos [1 ,11 ]
Dunlop, Sarah A. [1 ,2 ]
机构
[1] Minderoo Fdn, 171-173 Mounts Bay Rd, Perth, WA 6000, Australia
[2] Univ Western Australia, Sch Biol Sci, 35 Stirling Highway, Crawley, WA 6009, Australia
[3] Univ Western Australia, Sch Mol Sci, 35 Stirling Highway, Crawley, WA 6009, Australia
[4] Univ Western Australia, Hlth & Med Sci Lib, 35 Stirling Highway, Crawley, WA 6009, Australia
[5] Fiona Stanley Hosp, 11 Warren Dr, Murdoch, WA 6150, Australia
[6] UWA Med Sch, Fac Hlth & Med Sci, 35 Stirling Highway, Crawley, WA 6009, Australia
[7] Sir Charles Gairdner Hosp, Hosp Ave, Nedlands, WA 6009, Australia
[8] Univ Western Australia, Sch Human Sci, 35 Stirling Highway, Crawley, WA 6009, Australia
[9] Curtin Univ, Sch Mol & Life Sci, Kent St, Bentley, WA 6102, Australia
[10] Curtin Univ, Sch Popu Lat Hlth, Kent St, Bentley, WA 6102, Australia
[11] Royal Childrens Hosp, Murdoch Childrens Res Inst, 50 Flemington Rd, Parkville, Vic 3052, Australia
关键词
Human; Plastic; Plastic chemicals; Polymers; Additives; Exposure; Health; Toxicity; BISPHENOL-A; MICROPLASTICS; ASSOCIATION; CHEMICALS; QUALITY; FIBERS; DEBRIS; WATER;
D O I
10.1186/s13643-022-02010-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Global plastic production has increased exponentially since the 1960s, with more than 6300 million metric tons of plastic waste generated to date. Studies have found a range of human health outcomes associated with exposure to plastic chemicals. However, only a fraction of plastic chemicals used have been studied in vivo, and then often in animals, for acute toxicological effects. With many questions still unanswered about how long-term exposure to plastic impacts human health, there is an urgent need to map human in vivo research conducted to date, casting a broad net by searching terms for a comprehensive suite of plastic chemical exposures and the widest range of health domains. Methods: This protocol describes a scoping review that will follow the recommended framework outlined in the 2017 Guidance for the Conduct of Joanna Briggs Institute (JBI) Scoping Reviews, to be reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist. A literature search of primary clinical studies in English from 1960 onwards will be conducted in MEDLINE (Ovid) and EMBASE (Ovid) databases. References eligible for inclusion will be identified through a quality-controlled, multi-level screening process. Extracted data will be presented in diagrammatic and tabular form, with a narrative summary addressing the review questions. Discussion: This scoping review will comprehensively map the primary research undertaken to date on plastic exposure and human health. Secondary outputs will include extensive databases on plastic chemicals and human health outcomes/impacts.
引用
收藏
页数:9
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