Highly sensitive electrochemical impedance spectroscopy based sensor for Staphylococcus aureus detection

被引：7

作者：

Gu, Peng ^{[1
]}

Huang, Jing ^{[2
]}

Yao, Jiajiu ^{[3
]}

机构：

[1] Gen Hosp Yangtze River Shipping, Wuhan 430014, Hubei, Peoples R China

[2] Northeast Teachers Univ, Attached Hosp, Changchun 134000, Jilin, Peoples R China

[3] Air Force Mil Med Univ, Tangdu Hosp, Emergency Dept, Xian 710038, Shaanxi, Peoples R China

来源：

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2021年 / 16卷 / 12期

关键词：

Staphylococcus aureus; EIS; Biosensor; AuNPs; Prostatitis; BIOSENSOR;

D O I：

10.20964/2021.12.09

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Staphylococcus aureus is now considered one of the major pathogen of prostatitis. Its resistance to multiple drugs makes it difficult to treat, leading to a high morbidity and mortality rate. Therefore, it is imperative to establish sensitive, rapid and timely methods for the detection of Staphylococcus aureus. In this work, an electrochemical impedance spectroscopy sensor based on functionalized gold nanoparticles was constructed and realized for the rapid and highly sensitive analysis as well as the detection of Staphylococcus aureus. The experimental results demonstrated that the biosensor has a detection limit of 3 x 10(3) CFU/mL and a linear response range of 3 x 10(3) - 3 x 10(7) CFU/mL, which means a high sensitivity. In addition, the sensor has a short detection time, simple operation and high stability, which can be used for real-time detection.

引用

页数：11

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