Haliangicin, a novel antifungal metabolite produced by a marine myxobacterium 2. Isolation and structural elucidation

被引:165
作者
Fudou, R
Iizuka, T
Sato, S
Ando, T
Shimba, N
Yamanaka, S
机构
[1] Ajinomoto Co Inc, Cent Res Labs, Kawasaki Ku, Kawasaki, Kanagawa 2108681, Japan
[2] Ajinomoto Co Inc, Pharmaceut Res Labs, Kawasaki Ku, Kawasaki, Kanagawa 2108681, Japan
关键词
D O I
10.7164/antibiotics.54.153
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A novel antifungal antibiotic, haliangicin, was isolated from a culture broth of marine myxobacterium, Haliangium leuteum. The planar structure of haliangicin was elucidated by spectroscopic analyses and was shown to be a new polyunsaturated compound containing beta -methoxyacrylate moiety.
引用
收藏
页码:153 / 156
页数:4
相关论文
共 5 条
[1]   NATURAL ABUNDANCE N-15 NMR BY ENHANCED HETERONUCLEAR SPECTROSCOPY [J].
BODENHAUSEN, G ;
RUBEN, DJ .
CHEMICAL PHYSICS LETTERS, 1980, 69 (01) :185-189
[2]   Haliangicin, a novel antifungal metabolite produced by a marine myxobacterium 1. Fermentation and biological characteristics [J].
Fudou, R ;
Iizuka, T ;
Yamanaka, S .
JOURNAL OF ANTIBIOTICS, 2001, 54 (02) :149-152
[3]   Isolation of myxobacteria from the marine environment [J].
Iizuka, T ;
Jojima, Y ;
Fudou, R ;
Yamanaka, S .
FEMS MICROBIOLOGY LETTERS, 1998, 169 (02) :317-322
[4]  
Reichenbach H, 2000, SPR DESKT EDIT CHEM, P149
[5]  
RELCHENBACH H, 1993, MYXOBACTERIA 2, P347