Safety Assessment of Glycerin as Used in Cosmetics

被引:60
作者
Becker, Lillian C. [1 ]
Bergfeld, Wilma F. [1 ]
Belsito, Donald V. [1 ]
Hill, Ronald A. [1 ]
Klaassen, Curtis D. [1 ]
Liebler, Daniel C. [1 ]
Marks, James G., Jr. [1 ]
Shank, Ronald C. [1 ]
Slaga, Thomas J. [1 ]
Snyder, Paul W. [1 ]
Gill, Lillian J. [1 ]
Heldreth, Bart [1 ]
机构
[1] Cosmet Ingredient Rev, 1620L St NW,Suite 1200, Washington, DC 20036 USA
关键词
cosmetics; safety; glycerin; 4-NITROQUINOLINE; 1-OXIDE; PULMONARY TUMORIGENESIS; MUTAGENICITY; SPERMATOGENESIS; STEROIDOGENESIS; FERTILITY; TOXICITY; GLYCOL; LEVEL; RATS;
D O I
10.1177/1091581819883820
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This is a safety assessment of glycerin as used in cosmetics. Glycerin functions as a denaturant, fragrance ingredient, hair conditioning agent, humectant, oral care agent, oral health-care drug, skin protectant, skin conditioning agent-humectant, and viscosity-decreasing agent. The Cosmetic Ingredient Review Expert Panel (Panel) reviewed relevant animal and human data. The Panel concluded that glycerin is safe as a cosmetic ingredient in the practices of use and concentration described in this safety assessment.
引用
收藏
页码:6S / 22S
页数:17
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