In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe

被引：37

作者：

Jansen, W. T. A. ^{[1
]}

Verel, A. ^{[1
]}

Verhoef, J. ^{[1
]}

Milatovic, D. ^{[1
]}

机构：

[1] Univ Med Ctr, NL-3584 CX Utrecht, Netherlands

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 09期

关键词：

D O I：

10.1128/AAC.00100-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activity of telavancin was tested against 620 gram-positive isolates. For staphylococci, MICs at which 50 and 90% of isolates were inhibited (MIC50 and MIC90) were both 0.25 mu g/ml, irrespective of methicillin resistance. MIC50 and MIC90 were 0.25 and 0.5 mu g/ml for vancomycin-susceptible enterococci and 1 and 2 mu g/ml for vancomycin-resistant enterococci, respectively. Streptococcus pneumoniae, group A and B beta-hemolytic streptococci, and viridans streptococci were inhibited by <= 0.12 mu g/ml.

引用

页码：3420 / 3424

页数：5