Synthesis of 2-aminobenzothiazole via FeCl3-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water

被引：96

作者：

Ding, Qiuping ^{[1
,2
]}

Cao, Banpeng ^{[1
]}

Liu, Xianjin ^{[1
]}

Zong, Zhenzhen ^{[1
]}

Peng, Yi-Yuan ^{[2
]}

机构：

[1] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Peoples R China

[2] Key Lab Green Chem Jiangxi Prov, Nanchang 330022, Peoples R China

来源：

GREEN CHEMISTRY | 2010年 / 12卷 / 09期

基金：

中国国家自然科学基金;

关键词：

SUPERCRITICAL CARBON-DIOXIDE; CATALYZED INTRAMOLECULAR CYCLIZATION; FLUOROUS MEDIA; ROUTE; TRANSFORMATIONS; EFFICIENT; 2-ALKYNYLBENZALDOXIME; BENZOTHIAZOLES; STRATEGY; SOLVENT;

D O I：

10.1039/c0gc00123f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An FeCl3-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water is described, which provides an environmentally benign, efficient, and practical route for the generation of 2-aminobenzothiazole. This present tandem process shows broad substrate scope in the presence of octadecyltrimethylammonium chloride as a phase-transfer catalyst. In addition, the reaction media can be recovered and recycled without loss of efficiency.

引用

页码：1607 / 1610

页数：4

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