Hypervalent iodine(III) sulfonate mediated synthesis of imidazo[1,2-a]pyridines

被引：10
作者：
Huang, HY
Hou, RS
Wang, HM
Chen, LC [1 ]
机构：
[1] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Kaohsiung 807, Taiwan
[2] Chung Hwa Coll Med Technol, Tainan 717, Taiwan
来源：
JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2004年 / 51卷 / 06期
关键词：
hypervalent iodine(III) sulfonate; cyclocondensation; 2-aminopyridines;
D O I：
10.1002/jccs.200400201
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A direct and efficient method for the conversion of alkyl aryl ketones to imidazo[1,2-a]pyridines has been developed based on initial formation of alpha-organosulfonyloxy ketones and their subsequent cyclocondensation by 2-aminopyridines in one-pot conditions.
引用
收藏
页码：1377 / 1380
页数：4
相关论文
共 36 条
[1]  
ABIGNENTE E, 1989, J HETEROCYCLIC CHEM, V26, P1875
[2]   ORGANIC POLYVALENT IODINE COMPOUNDS [J].
BANKS, DF .
CHEMICAL REVIEWS, 1966, 66 (03) :243-&
[3]   IMIDAZO[1,2-B]PYRIDAZINES .18. SYNTHESES AND CENTRAL-NERVOUS-SYSTEM ACTIVITIES OF SOME 6-(CHLORO AND METHOXY)IMIDAZO[1,2-A]PYRIDINE, 7-(CHLORO AND METHOXY)IMIDAZO[1,2-A]PYRIDINE AND 8-(CHLORO AND METHOXY)IMIDAZO[1,2-A]PYRIDINE ANALOGS [J].
BARLIN, GB ;
DAVIES, LP ;
HARRISON, PW .
AUSTRALIAN JOURNAL OF CHEMISTRY, 1995, 48 (05) :1031-1038
[4]   SYNTHESIS OF NOVEL 8-ARYLIMIDAZO[1,2-A]PYRIDINES AND 8-ARYLIMIDAZO[1,5-A]PYRIDINES [J].
DAVEY, DD .
JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (09) :1863-1867
[5]   PHARMACOLOGICAL PROFILE OF RWJ-20085 - A NEW, POTENT, LONG-ACTING LOCAL-ANESTHETIC [J].
DUBINSKY, B ;
SHRIVER, DA ;
SANFILIPPO, PJ ;
PRESS, JB ;
TOBIA, AJ ;
ROSENTHALE, ME .
DRUG DEVELOPMENT RESEARCH, 1990, 21 (04) :277-289
[6]   IMIDAZO[1,2-A]PYRIDINE ANTHELMINTIC AND ANTIFUNGAL AGENTS [J].
FISHER, MH ;
LUSI, A .
JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (09) :982-&
[7]  
GALONS H, 1982, SYNTHESIS-STUTTGART, P1103
[8]  
Kang IJ, 2002, HETEROCYCLES, V57, P1
[9]   STUDIES ON KETENE AND ITS DERIVATIVES .119. REACTIONS OF HALOKETENES WITH 2-ARYLIDENEAMINOPYRIDINES [J].
KATAGIRI, N ;
KATO, T ;
NIWA, R .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1984, 21 (02) :407-412
[10]   Efficient syntheses of imidazolo[1,2-a]pyridines and -[2,1-a]isoquinolines [J].
Katritzky, AR ;
Qiu, GF ;
Long, QH ;
He, HY ;
Steel, PJ .
JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (26) :9201-9205
1234