The sebocyte culture: a model to study the pathophysiology of the sebaceous gland in sebostasis, seborrhoea and acne

被引:82
|
作者
Zouboulis, Christos C. [1 ,2 ,3 ,4 ]
Schagen, Silke [5 ]
Alestas, Theodosios [5 ,6 ]
机构
[1] Dessau Med Ctr, Dept Dermatol, D-06847 Dessau, Germany
[2] Dessau Med Ctr, Dept Venerol, D-06847 Dessau, Germany
[3] Dessau Med Ctr, Dept Allergol, D-06847 Dessau, Germany
[4] Dessau Med Ctr, Dept Immunol, D-06847 Dessau, Germany
[5] Charite, Lab Biogerontol Dermatopharmacol & Dermatoendocri, Inst Clin Pharmacol & Toxicol, D-13353 Berlin, Germany
[6] Natl & Capodistrian Univ Athens, Dept Dermatol, Andreas Sygros Hosp, Athens, Greece
关键词
sebocytes; sebaceous gland; skin physiology; sebostasis; seborrhea; acne; treatment; SZ95; hamster sebocytes; rat sebocytes; mouse sebocytes; hormones; hormone receptor; sebocyte development; Propionibacterium acnes; PPAR; cells; cultured; lipids; inflammation; drugs;
D O I
10.1007/s00403-008-0879-5
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Acne is the most common skin disease which affects millions of people worldwide. Seborrhea and sebostasis are major cosmetic problems but also lead occasionally to diseases. This article summarizes the data of newest research of sebostasis, seborrhoea and acne made possible through the development of human and animal sebocyte culture models.
引用
收藏
页码:397 / 413
页数:17
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