Lymphatic vasculature development - Current concepts

被引：48

作者：

Oliver, Guillermo ^{[1
]}

Srinivasan, R. Sathish ^{[1
]}

机构：

[1] St Jude Childrens Hosp, Dept Genet & Tumor Cell Biol, Memphis, TN 38105 USA

来源：

LYMPHATIC CONTINUUM REVISITED | 2008年 / 1131卷

关键词：

lymphangiogenesis; Prox1; Foxc2; ephrinB2; podoplanin;

D O I：

10.1196/annals.1413.006

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The recent identification of lymphatic endothelial cell-specific markers and the generation of mouse models harboring mutations in many genes that encode those markers have enabled us to begin to elucidate the developmental steps that go toward establishing the lymphatic vasculature network. Understanding these basic mechanisms of lymphatic development will improve our ability to diagnose, prevent, and ideally treat lymphatic disorders.

引用

页码：75 / 81

页数：7

共 46 条

[31] Mice null for Sox18 are viable and display a mild coat defect [J].

Pennisi, D ;

Bowles, J ;

Nagy, A ;

Muscat, G ;

Koopman, P .

MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (24) :9331-9336

[32] Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis [J].

Petrova, TV ;

Karpanen, T ;

Norrmén, C ;

Mellor, R ;

Tamakoshi, T ;

Finegold, D ;

Ferrell, R ;

Kerjaschki, D ;

Mortimer, P ;

Yla-Herttuala, S ;

Miura, N ;

Alitalo, K .

NATURE MEDICINE, 2004, 10 (09) :974-981

[33] Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor [J].

Petrova, TV ;

Mäkinen, T ;

Mäkelä, TP ;

Saarela, J ;

Virtanen, I ;

Ferrell, RE ;

Finegold, DN ;

Kerjaschki, D ;

Ylä-Herttuala, S ;

Alitalo, K .

EMBO JOURNAL, 2002, 21 (17) :4593-4599

[34] Cell tracing shows the contribution of the yolk sac to adult haematopoiesis [J].

Samokhvalov, Igor M. ;

Samokhvalova, Natalia I. ;

Nishikawa, Shin-ichi .

NATURE, 2007, 446 (7139) :1056-1061

[35] T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema [J].

Schacht, V ;

Ramirez, MI ;

Hong, YK ;

Hirakawa, S ;

Feng, D ;

Harvey, N ;

Williams, M ;

Dvorak, AM ;

Dvorak, HF ;

Oliver, G ;

Detmar, M .

EMBO JOURNAL, 2003, 22 (14) :3546-3556

[36] Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development [J].

Sebzda, Eric ;

Hibbard, Chris ;

Sweeney, Shawn ;

Abtahian, Farhad ;

Bezman, Natalie ;

Clemens, Gina ;

Maltzman, Jonathan S. ;

Cheng, Lan ;

Liu, Feiyan ;

Turner, Martin ;

Tybulewicz, Victor ;

Koretzky, Gary A. ;

Kahn, Mark L. .

DEVELOPMENTAL CELL, 2006, 11 (03) :349-361

[37] The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development [J].

Seo, Seungwoon ;

Fujita, Hideo ;

Nakano, Atsushi ;

Kang, Myengmo ;

Duarte, Antonio ;

Kume, Tsutomu .

DEVELOPMENTAL BIOLOGY, 2006, 294 (02) :458-470

[38] Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing [J].

Stadtfeld, M ;

Graf, T .

DEVELOPMENT, 2005, 132 (01) :203-213

[39] Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis [J].

Takashima, S ;

Kitakaze, M ;

Asakura, M ;

Asanuma, H ;

Sanada, S ;

Tashiro, F ;

Niwa, H ;

Miyazaki, J ;

Hirota, S ;

Kitamura, Y ;

Kitsukawa, T ;

Fujisawa, H ;

Klagsbrun, M ;

Hori, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (06) :3657-3662

[40]

VANDERPUTTE SCJ, 1975, ACTA MORPHOL NEER SC, V13, P245

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