Lymphatic vasculature development - Current concepts

被引：48

作者：

Oliver, Guillermo ^{[1
]}

Srinivasan, R. Sathish ^{[1
]}

机构：

[1] St Jude Childrens Hosp, Dept Genet & Tumor Cell Biol, Memphis, TN 38105 USA

来源：

LYMPHATIC CONTINUUM REVISITED | 2008年 / 1131卷

关键词：

lymphangiogenesis; Prox1; Foxc2; ephrinB2; podoplanin;

D O I：

10.1196/annals.1413.006

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The recent identification of lymphatic endothelial cell-specific markers and the generation of mouse models harboring mutations in many genes that encode those markers have enabled us to begin to elucidate the developmental steps that go toward establishing the lymphatic vasculature network. Understanding these basic mechanisms of lymphatic development will improve our ability to diagnose, prevent, and ideally treat lymphatic disorders.

引用

页码：75 / 81

页数：7

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