pH-responsive Capsaicin@chitosan nanocapsules for antibiofouling in marine applications

被引：92

作者：

Wang, Wenhui ^{[1
]}

Hao, Xiangping ^{[1
]}

Chen, Shougang ^{[1
]}

Yang, Zhaoqing ^{[1
]}

Wang, Caiyu ^{[1
]}

Yan, Ran ^{[1
]}

Zhang, Xiao ^{[2
]}

Liu, Hu ^{[3
,5
]}

Shao, Qian ^{[4
]}

Guo, Zhanhu ^{[3
]}

机构：

[1] Ocean Univ China, Sch Mat Sci & Engn, Qingdao 266100, Peoples R China

[2] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China

[3] Univ Tennessee, Dept Chem & Biomol Engn, Integrated Composites Lab, Knoxville, TN 37996 USA

[4] Shandong Univ Sci & Technol, Coll Chem & Environm Engn, Qingdao 266590, Shandong, Peoples R China

[5] Zhengzhou Univ, Key Lab Mat Proc & Mold, Natl Engn Res Ctr Adv Polymer Proc Technol, Minist Educ, Zhengzhou 450002, Henan, Peoples R China

来源：

POLYMER | 2018年 / 158卷

关键词：

Chitosan; Nanocapsules; Bacterial adhesion; CONTROLLED-RELEASE; POLYMERIC NANOPARTICLES; ANTIMICROBIAL ACTIVITY; GRAPHENE OXIDE; DELIVERY; COATINGS; MICROCAPSULES; FABRICATION; SYSTEM; POLYSACCHARIDES;

D O I：

10.1016/j.polymer.2018.10.067

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Capsaicin@chitosan nanocapsules (CAP@CS) were prepared by micro-emulsion method in this work. Through transition between protonation and deprotonation of pH sensitive amino groups in chitosan, capsaicin can be triggered for self-releasing by pH changes resulted from bacterial reproduction. The total amount of released CAP@CS at pH 4 is five times more than that at pH 8.5. The CAP@CS is able to maintain the pH responsive property after 15 cycles of dialysis at pH ranging from 4 to 8.5, indicating a good cycling stability of CAP@CS nanocapsules. The bacteriostasis efficiency of CAP@CS is still up to 82.23%, 81.13% and 80.43% against adhesion of Escherichia coli (E.coli), Staphylococcus aureus (S.aureus) and Pseudomons aeruginosa (P. aeruginosa), respectively, which is caused by the repeated protonation and deprotonation of amino groups in chitosan. The prepared CAP@CS nanocapsules enable a bio-driven, intelligent and pH responsive performance for antifouling in marine applications.

引用

页码：223 / 230

页数：8

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