Primitive Toll signalling: bugs, flies, worms and man

被引：42
作者：
Fallon, PG
Allen, RL
Rich, T
机构：
[1] Univ Cambridge, Dept Pathol, Div Microbiol & Parasitol, Cambridge CB2 1QP, England
[2] Univ Cambridge, Dept Pathol, Div Immunol, Cambridge CB2 1QP, England
[3] Univ Cambridge, Dept Pathol, Div Cellular Pathol, Cambridge CB2 1QP, England
来源：
TRENDS IN IMMUNOLOGY | 2001年 / 22卷 / 02期
关键词：
D O I：
10.1016/S1471-4906(00)01800-7
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A current area of interplay between immunologists, geneticists and developmental biologists concerns how Toll receptors assumed their dual roles in pathogen recognition end insect embryo patterning. The development of mechanisms that recognize and control infectious pathogens has been essential for the survival of metazoan organisms, Here, Padraic Fallen and colleagues consider the insights that might be gained from using nematodes to study immune signalling pathways.
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收藏
页码：63 / 66
页数：4
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