Comparison between two-dimensional synthetic mammography reconstructed from digital breast tomosynthesis and full-field digital mammography for the detection of T1 breast cancer

被引:62
作者
Choi, Ji Soo [1 ]
Han, Boo-Kyung [1 ]
Ko, Eun Young [1 ]
Ko, Eun Sook [1 ]
Hahn, Soo Yeon [1 ]
Shin, Jung Hee [1 ]
Kim, Min Jung [2 ]
机构
[1] Sungkyunkwan Univ, Dept Radiol, Samsung Med Ctr, Sch Med, 81 Irwon Ro Gangnam Gu, Seoul 135710, South Korea
[2] Sungkyunkwan Univ, Res Inst Radiol Sci, Dept Radiol, Coll Med, Seoul, South Korea
关键词
digital breast tomosynthesis; synthetic mammography; digital mammography; breast cancer; T1; stage; OBSERVER-PERFORMANCE; PROJECTION IMAGES; IN-SITU; WOMEN; RISK; DBT; CLASSIFICATION; MULTICENTER; COMBINATION; ULTRASOUND;
D O I
10.1007/s00330-015-4083-7
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
To evaluate the interpretative performance of two-dimensional (2D) synthetic mammography (SM) reconstructed from digital breast tomosynthesis (DBT) in the detection of T1-stage invasive breast cancers, compared to 2D full-field digital mammography (FFDM). This retrospective study enrolled 214 patients. For each patient, FFDM and DBT were performed between January and June 2013, and SM was reconstructed from DBT data. Three radiologists interpreted images and recorded visibility scores and morphologies of cancers. Diagnostic performances of SM and FFDM were compared. Percentages of detected cancers and visibility scores were compared for tumour size, and presence of calcifications for each observer. Observer sensitivity showed no difference for detection with SM and FFDM (P > 0.05). One observer showed a higher specificity (P = 0.02) and higher positive predictive value with SM (95 % CI 0.6-16.4), but the differences in the corresponding values between SM and FFDM for the other observers were not statistically significant. In subgroup analyses according to tumour size and presence of calcifications, percentages of detected cancers and visibility scores were not significantly different. Diagnostic performances of SM and FFDM are comparable for detecting T1-stage breast cancers. Therefore, our results indicate that SM may eliminate the need for additional FFDM during DBT-based imaging.
引用
收藏
页码:2538 / 2546
页数:9
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