The yeast Mediator complex and its regulation

被引：158
作者：
Björklund, S [1 ]
Gustafsson, CM
机构：
[1] Umea Univ, Dept Med Biochem, S-90187 Umea, Sweden
[2] Karolinska Inst, Dept Med Nutr, S-14186 Huddinge, Sweden
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 2005年 / 30卷 / 05期
关键词：
D O I：
10.1016/j.tibs.2005.03.008
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Mediator complex acts as a bridge, conveying regulatory information from enhancers and other control elements to the basal RNA polymerase II transcription machinery. Mediator is required for the regulated transcription of nearly all RNA polymerase II-dependent genes in Saccharomyces cerevisiae, and post-translational modifications of specific Mediator subunits can affect global patterns of gene transcription.
引用
收藏
页码：240 / 244
页数：5
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