Rad54, a Jack of all trades in homologous recombination

被引:118
|
作者
Tan, TLR
Kanaar, R
Wyman, C
机构
[1] Erasmus MC, Dept Cell Biol & Genet, NL-3000 DR Rotterdam, Netherlands
[2] Erasmus MC, Dept Radiat Oncol, NL-3000 DR Rotterdam, Netherlands
关键词
Rad54; Rad51; DNA double-strand break repair; chromatin remodeling; nucleosomes;
D O I
10.1016/S1568-7864(03)00070-3
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Homologous recombination mediates the transfer or exchange of genetic information between homologous DNA molecules. It plays important roles in central processes in the cell such as genome duplication and DNA damage repair. Recent experiments reveal the surprising versatility of one of its central actors, the Rad54 protein. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:787 / 794
页数:8
相关论文
共 50 条
  • [1] Rad54, a Jack of all trades in homologous recombination (vol 2, pg 787, 2003)
    Tan, TLR
    Kanaar, R
    Wyman, C
    DNA REPAIR, 2003, 2 (11) : 1293 - 1293
  • [2] Rad54, the motor of homologous recombination
    Mazin, Alexander V.
    Mazina, Olga M.
    Bugreev, Dmitry V.
    Rossi, Matthew J.
    DNA REPAIR, 2010, 9 (03) : 286 - 302
  • [3] Rad54 Phosphorylation Promotes Homologous Recombination by Balancing Rad54 Mobility and DNA Binding
    Lengert, Nicor
    Spies, Julian
    Drossel, Barbara
    BIOPHYSICAL JOURNAL, 2019, 116 (08) : 1406 - 1419
  • [4] Rad54: the Swiss Army knife of homologous recombination?
    Heyer, Wolf-Dietrich
    Li, Xuan
    Rolfsmeier, Michael
    Zhang, Xiao-Ping
    NUCLEIC ACIDS RESEARCH, 2006, 34 (15) : 4115 - 4125
  • [5] Rad54 dissociates homologous recombination intermediates by branch migration
    Dmitry V Bugreev
    Fumio Hanaoka
    Alexander V Mazin
    Nature Structural & Molecular Biology, 2007, 14 : 746 - 753
  • [6] Rad54 dissociates homologous recombination intermediates by branch migration
    Bugreev, Dmitry V.
    Hanaoka, Fumio
    Mazin, Alexander V.
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (08) : 746 - 753
  • [7] Somatic hypermutation does not require Rad54 and Rad54B-mediated homologous recombination
    Bross, L
    Wesoly, J
    Buerstedde, JM
    Kanaar, R
    Jacobs, H
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2003, 33 (02) : 352 - 357
  • [8] Homologous DNA pairing by human recombination factors Rad51 and Rad54
    Sigurdsson, S
    Van Komen, S
    Petukhovan, G
    Sung, P
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (45) : 42790 - 42794
  • [9] Analysis of mouse Rad54 expression and its implications for homologous recombination
    Essers, J
    Hendriks, RW
    Wesoly, J
    Beerens, CEMT
    Smit, B
    Hoeijmakers, JHJ
    Wyman, C
    Dronkert, MLG
    Kanaar, R
    DNA REPAIR, 2002, 1 (10) : 779 - 793
  • [10] Multiple interactions with the Rad51 recombinase govern the homologous recombination function of Rad54
    Raschle, M
    Van Komen, S
    Chi, P
    Ellenberger, T
    Sung, P
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (50) : 51973 - 51980