Identifying novel regulators of shoot meristem development

New organs are initiated throughout the life span of higher plants, This process occurs at the shoot meristem, which is initiated during embryogenesis and is later responsible for generating the above-ground portion of the plant, The shoot meristem can be thought of as having two zones, a central zone containing meristematic cells in an undifferentiated state, and a surrounding peripheral zone where cells enter a specific developmental pathway toward a differentiated state, Recent advances have revealed several genes that specifically regulate meristem development in Arabidopsis. However, extensive mutagenesis by several labs have identified only a handful of loci that appear to specifically regulate shoot meristem development, We have undertaken an enhancer/suppressor mutagenesis of an existing meristem mutant (clv1) and have identified novel regulators of meristem development.