Synthesis and resolution of planar-chiral derivatives of 4-(Dimethylamino)pyridine

被引：36
|
作者：
Wurz, Ryan P. [1 ]
Lee, Elaine C. [1 ]
Ruble, J. Craig [1 ]
Fu, Gregory C. [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2007年 / 349卷 / 14-15期
关键词：
asymmetric catalysis; asymmetric synthesis; heterocycles; homogeneous catalysis;
D O I：
10.1002/adsc.200700219
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A safer and more efficient method for the synthesis of planar-chiral 4-(dimethylamino)pyridine (DMAP) derivatives has been developed. Racemic mixtures of the complexes can be resolved via classical resolution with commercially available tartaric acids.
引用
收藏
页码：2345 / 2352
页数：8
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