Effect of Vitamin Supplementation in Patients of Congestive Heart Failure Deficient in Vitamin D: A Study at a Tertiary Care Center of North India

被引：4
作者：
Mohanty, Vivek [1 ,2 ]
Pathania, Monika [1 ]
Bhasi, Ankith [1 ]
机构：
[1] All India Inst Med Sci, Dept Med, Rishikesh, Uttaranchal, India
[2] All India Inst Med Sci, Dept Med, Room 225,Bldg 84, Rishikesh 249203, Uttaranchal, India
来源：
ANNALS OF AFRICAN MEDICINE | 2022年 / 21卷 / 02期
关键词：
Left ventricular end diastolic diameter; left ventricular ejection fraction; NT-pro BNP; Vitamin-D; WHODAS; 2.0; score; NATRIURETIC PEPTIDE; PARATHYROID-HORMONE;
D O I：
10.4103/aam.aam_70_20
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction: Heart Failure is a leading cause of mortality worldwide including India. Most cross sectional studies have demonstrated heart failure is associated with deficiency of essential micronutrients including Vitamin D which may play a important role in pathogenesis of ventricular remodelling in heart failure. Aim: Our study performed aimed to determine the effect of supplementation in patients of Heart Failure presenting with Vitamin D deficiency to our institute on severity of Heart Failure. Design and Method: 97 patients of Heart failure coming to our institute were given conventional therapies for Heart Failure along with Vitamin supplementation based on serum Vitamin D levels and followed up for 3 months. Results: Patient of Heart failure having Vitamin D deficiency had significant reduction in cardiac biomarkers (NT-pro BNP levels), improvement in Left ventricular ejection fraction (LVEF) and more favourable reverse remodelling determined by Left ventricular end diastolic and systolic diameter (LVEDD & LVESD) though quality of life determined by WHODAS 2.0 score did not changed following 12 weeks supplementation of High Dose Vitamin D. Conclusion: Recognising and treatment of Vitamin D deficiency may determine long term prognosis in patients of Heart Failure.
引用
收藏
页码：107 / 112
页数：6
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