Balance Dysfunction in Parkinson's Disease

被引：90

作者：

Rinalduzzi, Steno ^{[1
]}

Trompetto, Carlo ^{[2
]}

Marinelli, Lucio ^{[2
]}

Alibardi, Alessia ^{[3
,4
]}

Missori, Paolo ^{[5
]}

Fattapposta, Francesco ^{[6
]}

Pierelli, Francesco ^{[4
,7
,8
]}

Curra, Antonio ^{[3
,4
]}

机构：

[1] Sandro Pertini Hosp, I-00157 Rome, Italy

[2] Univ Genoa, Inst Neurol, Dept Neurosci Rehabil Ophthalmol Genet Maternal &, I-16132 Genoa, Italy

[3] Univ Roma La Sapienza, Acad Neurol Unit, A Fiorini Hosp, I-04019 Terracina, Italy

[4] Univ Roma La Sapienza, Dept Med Surg Sci & Biotechnol, I-04019 Terracina, Italy

[5] Univ Roma La Sapienza, Dept Neurol & Psychiat, Policlin Umberto I, Neurosurg Unit, I-00161 Rome, Italy

[6] Univ Roma La Sapienza, Dept Neurol & Otolaryngol, Policlin Umberto I, Neurol Unit, I-00185 Rome, Italy

[7] Univ Roma La Sapienza, ICOT, Acad Neurorehabil Unit, I-04100 Latina, Italy

[8] INM Neuromed IRCCS, I-86077 Pozzilli, Italy

来源：

BIOMED RESEARCH INTERNATIONAL | 2015年 / 2015卷

关键词：

GALVANIC VESTIBULAR STIMULATION; AUTOMATIC POSTURAL RESPONSES; VISUAL CONTROL; SET; MOVEMENTS; REFLEXES; TRUNK; ALZHEIMERS; DEFICITS; STABILIZATION;

D O I：

10.1155/2015/434683

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment process. All or some of the components of this system may be dysfunctional in Parkinsonian patients, rendering postural instability one of the most disabling features of Parkinson's disease (PD). Balance control is critical for moving safely in and adapting to the environment. PD induces a multilevel impairment of this function, therefore worsening the patients' physical and psychosocial disability. In this review, we describe the complex ways in which PD impairs posture and balance, collecting and reviewing the available experimental evidence.

引用

页数：10

共 67 条

[1] Proprioceptive control of posture: a review of new concepts [J].