The Experience of Older Patients With Cancer in Phase 1 Clinical Trials: A Qualitative Case Series

被引：10

作者：

Kvale, Elizabeth A. ^{[1
,2
,3
,4
]}

Woodby, Lesa ^{[1
,2
,3
,4
]}

Williams, Beverly Rosa ^{[1
,2
,3
,4
]}

机构：

[1] Birmingham Atlanta Geriatr Res Educ & Clin Ctr GR, Birmingham, AL USA

[2] Birmingham VA Med Ctr, Birmingham, AL USA

[3] Univ Alabama Birmingham, Ctr Aging, Birmingham, AL USA

[4] Univ Alabama Birmingham, Div Gerontol Geriatr & Palliat Care, Birmingham, AL USA

来源：

AMERICAN JOURNAL OF HOSPICE & PALLIATIVE MEDICINE | 2010年 / 27卷 / 07期

关键词：

aging; cancer psychosocial aspects; hope; illness and disease experiences; older people; pain; research participation; social support; symptom management; RANDOMIZED CONTROLLED-TRIAL; OF-LIFE; I TRIALS; BODY-IMAGE; HOPE; PARTICIPATION; PERCEPTIONS; CHEMOTHERAPY; EXPECTATIONS; PERSPECTIVE;

D O I：

10.1177/1049909110365072

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

This article explores the experiences of older patients with cancer in phase 1 clinical trials. Conducting a case series of face-to-face, in-depth, open-ended interviews and using qualitative methods of analysis, we find that the psychosocial process of social comparison is relevant for understanding older adults' phase 1 clinical trial participation. Social comparison influences decisions to enroll in a phase 1 clinical trial, shapes perceptions of supportive care needs, and encourages the utilization of hope. Additional research should develop strategies for addressing supportive care needs among this patient cohort whose use of social comparison can inhibit articulation of pain, suffering, and symptom burden as well as use of informal support systems.

引用

页码：474 / 481

页数：8

共 61 条

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