Respiratory-gated micro-CT using a carbon nanotube based micro-focus field emission x-ray source

被引：4

作者：

Cao, Guohua ^{[1
]}

Lee, Yueh Z. ^{[1
,2
]}

Liu, Zejian ^{[1
]}

Rajaram, Ramya ^{[3
]}

Peng, Rui ^{[3
]}

Calderon-Colon, Xiomara ^{[3
]}

An, Lei ^{[1
]}

Wang, Peng ^{[1
]}

Phan, Tuyen ^{[4
]}

Lalush, David ^{[5
]}

Lu, Jianping ^{[1
,3
]}

Zhou, Otto ^{[1
,3
,6
]}

机构：

[1] Univ N Carolina, Dept Phys & Astron, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Radiol, Chapel Hill, NC 27599 USA

[3] Univ N Carolina, Curriculum Appl & Mat Sci, Chapel Hill, NC 27599 USA

[4] Univ N Carolina, Dept Biomed Engn, Chapel Hill, NC 27599 USA

[5] North Carolina State Univ, Dept Biomed Engn, Raleigh, NC 27695 USA

[6] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA

来源：

MEDICAL IMAGING 2008: PHYSICS OF MEDICAL IMAGING, PTS 1-3 | 2008年 / 6913卷

关键词：

micro-CT; in vivo imaging; respiratory gating; x-ray source; carbon nanotube;

D O I：

10.1117/12.770592

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A prototype physiologically gated micro-computed tomography (micro-CT) system based on a field emission micro-focus x-ray source has been developed for in vivo imaging of small animal models. The novel x-ray source can generate radiation with a programmable waveform that can be readily synchronized and gated with non-periodic physiological signals. The system performance is evaluated using phantoms and sacrificed and anesthetized mouse models. Prospective respiratory-gated CT images of anesthetized free-breathing mice are collected using this scanner at 100 msec temporal resolution and 101p/mm of 10% system MTF.

引用

页数：11

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