Synthesis and characterization of 3-[(2-{(2-(hydrazinocarbonyl)ethyl]sulfanyl}phenyl)amino]propanehydrazide derivatives

被引：0

作者：

Rutkauskas, Kestutis ^{[1
]}

Tumosiene, Ingrida ^{[1
]}

Mikulskiene, Gema ^{[2
]}

Kantminiene, Kristina ^{[3
]}

Beresnevicius, Zigmuntas J. ^{[1
]}

机构：

[1] Kaunas Univ Technol, Dept Organ Chem, LT-50254 Kaunas, Lithuania

[2] Vilnius Univ, Inst Biochem, LT-08662 Vilnius, Lithuania

[3] Kaunas Univ Technol, Dept Gen Chem, LT-50254 Kaunas, Lithuania

来源：

CHEMIJA | 2011年 / 22卷 / 04期

关键词：

hydrazide; hydrazone; pyrrole; pyrazole; NMR; NMR CHEMICAL-SHIFTS; ANTIMICROBIAL ACTIVITIES; ROTATIONAL BARRIERS; C-13; HYDRAZONE; PYRAZOLES; PROTONATION; IR;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of 3-[(2-{(2-(hydrazinecarbonyl)ethyl]sulfanyl}pheny)amino]propanehydrazide derivatives containing identically ortho-NH/S-substituted benzene moiety were synthesized. The structure of the obtained compounds was proved by combining elemental analysis, mass spectrometry, and H-1 C-13 NMR spectroscopy. The H-1/C-13 2D (HETCOR), H-1/H-1 2D (COSY), DEPT (C-13), NOE (H-1) NMR methods and molecular modeling (MM2) were used for structure elucidation in more complicated cases. Supplementary sets of resonances, observed in the H-1 and C-13 NMR spectra of the majority of synthesized compounds, are explained in terms of peculiar structural features.

引用

页码：238 / 247

页数：10

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