Catalyst Free Indirect Friedlander Synthesis of Substituted Quinolines from Alcohols in PEG-400

被引：10

作者：

Wu, Fang-Wen ^{[2
]}

Hou, Rei-Sheu ^{[1
]}

Wang, Huey-Min ^{[1
]}

Kang, Iou-Jiun ^{[3
]}

Chen, Ling-Ching ^{[2
]}

机构：

[1] Chung Hwa Coll Med Technol, Tainan 717, Taiwan

[2] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Coll Pharm, Kaohsiung 807, Taiwan

[3] Yung Shin Pharmaceut, Dept Res & Dev, Taichung, Taiwan

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2012年 / 59卷 / 04期

关键词：

Friedlander annulation; Quinoxaline; Poly(ethylene glycol); POLY(ETHYLENE GLYCOL) PEG; ONE-STEP SYNTHESIS; 2-AMINOBENZYL ALCOHOL; RECYCLABLE REACTION; IONIC LIQUIDS; SOLVENT; DERIVATIVES; EFFICIENT; KETONES; POLYMERS;

D O I：

10.1002/jccs.201100404

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of substituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding aminoalcohol and ketone using PEG-400 as reaction medium in the presence of a base, without any transition-metal catalyst.

引用

页码：535 / 539

页数：5

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