Catalyst Free Indirect Friedlander Synthesis of Substituted Quinolines from Alcohols in PEG-400

被引：10
|
作者：
Wu, Fang-Wen [2 ]
Hou, Rei-Sheu [1 ]
Wang, Huey-Min [1 ]
Kang, Iou-Jiun [3 ]
Chen, Ling-Ching [2 ]
机构：
[1] Chung Hwa Coll Med Technol, Tainan 717, Taiwan
[2] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Coll Pharm, Kaohsiung 807, Taiwan
[3] Yung Shin Pharmaceut, Dept Res & Dev, Taichung, Taiwan
来源：
JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2012年 / 59卷 / 04期
关键词：
Friedlander annulation; Quinoxaline; Poly(ethylene glycol); POLY(ETHYLENE GLYCOL) PEG; ONE-STEP SYNTHESIS; 2-AMINOBENZYL ALCOHOL; RECYCLABLE REACTION; IONIC LIQUIDS; SOLVENT; DERIVATIVES; EFFICIENT; KETONES; POLYMERS;
D O I：
10.1002/jccs.201100404
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of substituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding aminoalcohol and ketone using PEG-400 as reaction medium in the presence of a base, without any transition-metal catalyst.
引用
收藏
页码：535 / 539
页数：5
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