Familial Aggregation of Panic Disturbances in Parkinson's Disease

被引：4

作者：

Pontone, Gregory M. ^{[1
]}

Palanci, Justin

Bienvenu, O. Joseph

Liang, Kung-Yee

Nestadt, Gerald

Rabins, Peter V.

Williams, James R.

Marsh, Laura

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, Baltimore, MD 21205 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2011年 / 23卷 / 04期

基金：

美国国家卫生研究院;

关键词：

ATTACK-LIKE EPISODES; ANXIETY DISORDERS; EARLY-ONSET; HETEROGENEITY; COMORBIDITY; PREVALENCE; POPULATION; SUBTYPES; RISK;

D O I：

10.1176/jnp.23.4.jnp417

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Panic disorder has an elevated prevalence in Parkinson's disease (PD). To explore the basis for this co-occurrence, the familial aggregation of panic disorder was examined in patients with PD. Probands and relatives of patients with PD and panic disorder (PD-PANIC; N=20, N=115) and control probands with PD and no active psychiatric illness (PD-NA; N=17, N=108) were interviewed by phone, using a structured interview to determine panic status. Lifetime prevalence of panic and "panic-like" disorders was higher in PD-PANIC than in PD-NA relatives. Panic and "panic-like" disorders are familial disorders in PD. (The Journal of Neuropsychiatry and Clinical Neurosciences 2011; 23:417-424)

引用

页码：417 / 424

页数：8

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