[1] Univ Toronto, Dept Anesthesiol & Pain Med, Toronto, ON, Canada
[2] Toronto Gen Hosp, Dept Anesthesia & Pain Management, EN 429,200 Elizabeth St, Toronto, ON M5G 2C4, Canada
[3] Univ Turin, Dept Anesthesiol & Intens Care, Univ Hosp San Luigi Gonzaga, Turin, Italy
[4] Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada