We have successfully synthesized a new 1222-type Y-based niobio-cuprate for the first time with the chemical composition, NbSr(2)(Y(1.5)Ce(0.5))Cu(2)O(10) by a high-pressure and high-temperature (HPHT) technique under different synthesis conditions. Good quality ( nearly single-phase) Nb1222Y polycrystalline sample was synthesized at 1,450 degrees C and 6 GPa for 2 h. It crystallizes in a tetragonal symmetry of space group I4/mmm with lattice parameters a = b = 3.863(2) angstrom and c = 28.687(5) angstrom, which is isostructural with the corresponding Ru1222Y (RuSr2 (Y(1.5)Ce(0.5))Cu(2)O(10)) phase. The dc-magnetic susceptibility measurements show a mixed magnetic state at similar to 29 K, which is apparently associated with magneto-superconductivity. The magnetic moment ( M) versus field ( H) curve of Nb1222Y sample measured at 1.8 K looks like a hybrid and it normally ensembles for both superconducting and a ferromagnetic curve. As the field increases, a low field diamagnetic signal emerges. However, temperature dependence of electrical resistivity of Nb1222Y did not show superconductivity, but semiconducting nature with a relatively large magnetoresistance (similar to 6% at almost entire region). No specific heat anomaly was observed at the vicinity of the transition temperature.