Chemical mapping of the distribution of viruses into infected bacteria with a photothermal method

被引:113
作者
Dazzi, A. [1 ]
Prazeres, R. [1 ]
Glotin, F. [1 ]
Ortega, J. M. [1 ]
Al-Sawaftah, M. [1 ]
de Frutos, M. [2 ]
机构
[1] Univ Paris 11, CLIO LCP, F-91405 Orsay, France
[2] Univ Paris 11, Phys Solides Lab, F-91405 Orsay, France
关键词
microscopy; spectroscopy; nanoscience; cell imaging;
D O I
10.1016/j.ultramic.2007.10.008
中图分类号
TH742 [显微镜];
学科分类号
摘要
We show that an infrared spectromicroscopy method based on a photo-thermal effect, is able to localize single viruses as well when they are isolated and when they are located inside the bacteria they have infected. In this latter case, although the topography performed by an AFM cannot image the viruses, the AFMIR is able to do so. In addition, we are able to determine different stages of the bacteria infection. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:635 / 641
页数:7
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