Skin lesions in diabetic patients

被引:24
作者
Foss, NT [1 ]
Polon, DP [1 ]
Takada, MH [1 ]
Foss-Freitas, MC [1 ]
Foss, MC [1 ]
机构
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Hosp Clin, Dept Clin Med, BR-14049900 Ribeirao Preto, Brazil
来源
REVISTA DE SAUDE PUBLICA | 2005年 / 39卷 / 04期
关键词
skin diseases; dermatomycoses; diabetes mellitus; metabolic control;
D O I
10.1590/S0034-89102005000400024
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective It is yet unknown the relationship between diabetes and determinants or triggering factors of skin lesions in diabetic patients. The purpose of the present study was to investigate the presence of unreported skin lesions in diabetic patients and their relationship with metabolic control of diabetes. Methods A total of 403 diabetic patients, 31% type I and 69% type 2, underwent dermatological examination in an outpatient clinic of a university hospital. The endocrine-metabolic evaluation was carried out by an endocrinologist followed by the dermatological evaluation by a dermatologist. The metabolic control of 136 patients was evaluated using glycated hemoglobin. Results High number of dermophytosis (82.6%) followed by different types of skin lesions such as acne and actinic degeneration (66.7%), pyoderma (5916), cutaneous tumors (3%) and necrobiosis lipoidic (1 016) were found. Among the most common skin lesions in diabetic patients, confirmed by histopathology, there were seen necrobiosis lipoidic (2 cases, 0.4%), diabetic dermopathy (5 cases, 1.2%) and foot ulcerations (3 cases, 0.7%). Glycated hemoglobin was 7.2% in both type I and 2 patients with adequate metabolic control and 11.9% and 12.7% in type I and 2 diabetic patients, respectively, with inadequate metabolic controls. A higher prevalence of dermatophytoses was seen in the both groups with inadequate metabolic control. Conclusions The results showed a high prevalence of skin lesions in diabetic patients, especially dermatophytoses. Thus, poor metabolic control of diabetes increases patient susceptibility to skin infections.
引用
收藏
页码:677 / 682
页数:6
相关论文
共 21 条
[1]   Interactions of the skin and nervous system [J].
Ansel, JC ;
Armstrong, CA ;
Song, I ;
Quinlan, KL ;
Olerud, JE ;
Caughman, SW ;
Bunnett, NW .
JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, VOL 2, NO 1, AUGUST 1997, 1997, :23-26
[2]   RELATIONSHIP BETWEEN GLYCEMIC CONTROL AND COLLAGEN-LINKED ADVANCED GLYCOSYLATION END-PRODUCTS IN TYPE-I DIABETES [J].
BEISSWENGER, PJ ;
MOORE, LL ;
CURPHEY, TJ .
DIABETES CARE, 1993, 16 (05) :689-694
[3]  
Bub JL, 2003, DERMATOLOGY GEN MED, V6th, P1651
[4]   INSULIN RESISTANCE - A MULTIFACETED SYNDROME RESPONSIBLE FOR NIDDM, OBESITY, HYPERTENSION, DYSLIPIDEMIA, AND ATHEROSCLEROTIC CARDIOVASCULAR-DISEASE [J].
DEFRONZO, RA ;
FERRANNINI, E .
DIABETES CARE, 1991, 14 (03) :173-194
[5]  
Delamaire M, 1997, DIABETIC MED, V14, P29, DOI 10.1002/(SICI)1096-9136(199701)14:1<29::AID-DIA300>3.0.CO
[6]  
2-V
[7]   ACCUMULATION OF MAILLARD REACTION-PRODUCTS IN SKIN COLLAGEN IN DIABETES AND AGING [J].
DYER, DG ;
DUNN, JA ;
THORPE, SR ;
BAILIE, KE ;
LYONS, TJ ;
MCCANCE, DR ;
BAYNES, JW .
JOURNAL OF CLINICAL INVESTIGATION, 1993, 91 (06) :2463-2469
[8]  
EISENBARTH GS, 1986, NEW ENGL J MED, V314, P1360
[9]  
Gupta AK, 1998, BRIT J DERMATOL, V139, P665, DOI 10.1046/j.1365-2133.1998.02464.x
[10]   Primary care: Infections in patients with diabetes mellitus [J].
Joshi, N ;
Caputo, GM ;
Weitekamp, MR ;
Karchmer, AW .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (25) :1906-1912