Understanding racial differences in obesity and metabolic syndrome traits

被引:14
作者
Fernández, JR
Allison, DB
机构
[1] Univ Alabama Birmingham, Clin Nutr Res Ctr, Dept Biostat, Sect Stat Genet, Birmingham, AL 35294 USA
[2] Univ Alabama Birmingham, Dept Nutr Sci, Birmingham, AL 35294 USA
关键词
obesity; racial differences; genetic admixture;
D O I
10.1301/nr.2003.sept.316-319
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Epidemiologic data demonstrate a positive association between obesity and certain measures related to the metabolic syndrome that differ among individuals of different ethnic/racial backgrounds. The effect of genetic and environmental factors on these differences is not completely understood, however, insightful information can be obtained by taking into account the degree of ancestral admixture in populations.
引用
收藏
页码:316 / 319
页数:4
相关论文
共 17 条
[1]  
Bell AC, 2002, AM J EPIDEMIOL, V155, P346, DOI 10.1093/aje/155.4.346
[2]   Association of African genetic admixture with resting metabolic rate and obesity among women [J].
Fernández, JR ;
Shriver, MD ;
Beasley, TM ;
Rafla-Demetrious, N ;
Parra, E ;
Albu, J ;
Nicklas, B ;
Ryan, AS ;
McKeigue, PM ;
Hoggart, CL ;
Weinsier, RL ;
Allison, DB .
OBESITY RESEARCH, 2003, 11 (07) :904-911
[3]   Fat distribution and insulin response in prepubertal African American and white children [J].
Gower, BA ;
Nagy, TR ;
Trowbridge, CA ;
Dezenberg, C ;
Goran, MI .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 67 (05) :821-827
[4]   Using genetic admixture to explain racial differences in insulin-related phenotypes [J].
Gower, BA ;
Fernández, JR ;
Beasley, TM ;
Shriver, MD ;
Goran, MI .
DIABETES, 2003, 52 (04) :1047-1051
[5]   Contribution of insulin secretion and clearance to glucose-induced insulin concentration in African-American and Caucasian children [J].
Gower, BA ;
Granger, WM ;
Franklin, F ;
Shewchuk, RM ;
Goran, MI .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (05) :2218-2224
[6]   Relationship between plasma glucose concentrations and native Hawaiian ancestry: the native Hawaiian health research project [J].
Grandinetti, A ;
Kaholokula, JK ;
Chang, HK ;
Chen, R ;
Rodriguez, BL ;
Melish, JS ;
Curb, JD .
INTERNATIONAL JOURNAL OF OBESITY, 2002, 26 (06) :778-782
[7]   Prevalence of glucose intolerance among native Hawaiians in two rural communities [J].
Grandinetti, A ;
Chang, HK ;
Mau, MK ;
Curb, JD ;
Kinney, EK ;
Sagum, R ;
Arakaki, RF .
DIABETES CARE, 1998, 21 (04) :549-554
[8]   Increased insulin resistance and insulin secretion in nondiabetic African-Americans and Hispanics compared with non-Hispanic whites - The insulin resistance atherosclerosis study [J].
Haffner, SM ;
DAgostino, R ;
Saad, MF ;
Rewers, M ;
Mykkanen, L ;
Selby, J ;
Howard, G ;
Savage, PJ ;
Hamman, RF ;
Wagenknecht, LE ;
Bergman, RN .
DIABETES, 1996, 45 (06) :742-748
[9]   Ability of alternative indices of insulin sensitivity to predict cardiovascular risk: Comparison with the "minimal model" [J].
Howard, G ;
Bergman, R ;
Wagenknecht, LE ;
Haffner, SM ;
Savage, PJ ;
Saad, MF ;
Laws, A ;
D'Agostino, RB .
ANNALS OF EPIDEMIOLOGY, 1998, 8 (06) :358-369
[10]   HOW GOOD A MARKER IS INSULIN LEVEL FOR INSULIN-RESISTANCE [J].
LAAKSO, M .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1993, 137 (09) :959-965