Practical synthesis of sultams via sulfonamide dianion alkylation: Application to the synthesis of chiral sultams

被引：48

作者：

Lee, JM ^{[1
]}

Zhong, YL ^{[1
]}

Reamer, RA ^{[1
]}

Askin, D ^{[1
]}

机构：

[1] Merck Res Labs, Dept Proc Res, Rahway, NJ 07065 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 22期

关键词：

D O I：

10.1021/ol0356183

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[graphics] A practical synthesis of sultams was developed via intramolecular sulfonamide dianion alkylation. This method has been applied toward the synthesis of chiral sultams, which are synthetically valuable as chiral auxiliaries.

引用

页码：4175 / 4177

页数：3

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