A place for thioether chemistry in cellular copper ion recognition and trafficking

被引：201
作者：
Davis, Anna V.
O'Halloran, Thomas V. [1 ]
机构：
[1] Northwestern Univ, Dept Chem & Biochem, Evanston, IL 60208 USA
[2] Northwestern Univ, Dept Mol Biol & Cell Biol, Evanston, IL 60208 USA
来源：
NATURE CHEMICAL BIOLOGY | 2008年 / 4卷 / 03期
关键词：
D O I：
10.1038/nchembio0308-148
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Over the last decade, cysteine thiolate ligands have been shown to be critical to the Cu(I) (cuprous) binding chemistry of many cytosolic metallochaperone and metalloregulatory proteins involved in copper physiology. More recently, the thioether group of methionine has begun to emerge as an important Cu(I) ligand for trafficking proteins in more oxidizing cellular environments.
引用
收藏
页码：148 / 151
页数：4
相关论文
共 31 条
  • [11] Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
    Changela, A
    Chen, K
    Xue, Y
    Holschen, J
    Outten, CE
    O'Halloran, TV
    Mondragón, A
    [J]. SCIENCE, 2003, 301 (5638) : 1383 - 1387
  • [12] An atypical linear Cu(I)-S2 center constitutes the high-affinity metal-sensing site in the CueR metalloregulatory protein
    Chen, K
    Yuldasheva, S
    Penner-Hahn, JE
    O'Halloran, TV
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (40) : 12088 - 12089
  • [13] Copper trafficking to the mitochondrion and assembly of copper metalloenzymes
    Cobine, Paul A.
    Pierrel, Fabien
    Winge, Dennis R.
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2006, 1763 (07): : 759 - 772
  • [14] Copper-induced conformational changes in the N-terminal domain of the Wilson disease copper-transporting ATPase
    DiDonato, M
    Hsu, HF
    Narindrasorasak, S
    Que, L
    Sarkar, B
    [J]. BIOCHEMISTRY, 2000, 39 (07) : 1890 - 1896
  • [15] Transition metal speciation in the cell: Insights from the chemistry of metal ion receptors
    Finney, LA
    O'Halloran, TV
    [J]. SCIENCE, 2003, 300 (5621) : 931 - 936
  • [16] Preparation, spectroscopic, characterization, and molecular structure of copper(I) aliphatic thiolate complexes
    Fujisawa, K
    Imai, S
    Kitajima, N
    Moro-oka, Y
    [J]. INORGANIC CHEMISTRY, 1998, 37 (02) : 168 - 169
  • [17] PREPARATION, CRYSTAL-STRUCTURE, AND SPECTROSCOPIC CHARACTERIZATION OF [NET4]2[CU(SPH)3]
    GARNER, CD
    NICHOLSON, JR
    CLEGG, W
    [J]. INORGANIC CHEMISTRY, 1984, 23 (14) : 2148 - 2150
  • [18] Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination
    Jiang, JF
    Nadas, IA
    Kim, MA
    Franz, KJ
    [J]. INORGANIC CHEMISTRY, 2005, 44 (26) : 9787 - 9794
  • [19] CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator
    Liu, Tong
    Ramesh, Arati
    Ma, Zhen
    Ward, Sarah K.
    Zhang, Limei
    George, Graham N.
    Talaat, Adel M.
    Sacchettini, James C.
    Giedroc, David P.
    [J]. NATURE CHEMICAL BIOLOGY, 2007, 3 (01) : 60 - 68
  • [20] Yeast Sco1, a protein essential for cytochrome c oxidase function is a Cu(I)-binding protein
    Nittis, T
    George, GN
    Winge, DR
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (45) : 42520 - 42526
1234