BIOCHEMISTRY How two amino acids become one

被引:2
作者
Ragsdale, Stephen W. [1 ]
机构
[1] Univ Michigan, Sch Med, Dept Biol Chem, Ann Arbor, MI 48109 USA
关键词
GENETIC-CODE; TRANSFER-RNA; PYRROLYSINE; UAG;
D O I
10.1038/471583a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Twenty amino acids form the basis of all proteins, but another two genetically encoded amino acids have also been discovered. The biosynthesis of one of these, pyrrolysine, has now been elucidated. See Letterp.647
引用
收藏
页码:583 / 584
页数:2
相关论文
共 10 条
  • [1] Direct charging of tRNACUA with pyrrolysine in vitro and in vivo
    Blight, SK
    Larue, RC
    Mahapatra, A
    Longstaff, DG
    Chang, E
    Zhao, G
    Kang, PT
    Church-Church, KB
    Chan, MK
    Krzycki, JA
    [J]. NATURE, 2004, 431 (7006) : 333 - 335
  • [2] Frey PA, 2008, CRIT REV BIOCHEM MOL, V43, P63, DOI [10.1080/10409230701829169, 10.1080/10409230701829169 ]
  • [3] The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine
    Gaston, Marsha A.
    Zhang, Liwen
    Green-Church, Kari B.
    Krzycki, Joseph A.
    [J]. NATURE, 2011, 471 (7340) : 647 - U131
  • [4] A new UAG-encoded residue in the structure of a methanogen methyltransferase
    Hao, B
    Gong, WM
    Ferguson, TK
    James, CM
    Krzycki, JA
    Chan, MK
    [J]. SCIENCE, 2002, 296 (5572) : 1462 - 1466
  • [5] Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases
    Krzycki, JA
    [J]. CURRENT OPINION IN CHEMICAL BIOLOGY, 2004, 8 (05) : 484 - 491
  • [6] A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine
    Longstaff, David G.
    Larue, Ross C.
    Faust, Joseph E.
    Mahapatra, Anirban
    Zhang, Liwen
    Green-Church, Kari B.
    Krzycki, Joseph A.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (03) : 1021 - 1026
  • [7] Adding pyrrolysine to the Escherichia coli genetic code
    Namy, Olivier
    Zhou, Yu
    Gundllapalli, Sarath
    Polycarpo, Carla R.
    Denise, Alain
    Rousset, Jean-Pierre
    Soll, Dieter
    Ambrogelly, Alexandre
    [J]. FEBS LETTERS, 2007, 581 (27) : 5282 - 5288
  • [8] An aminoacyl-tRNA synthetase that specifically activates pyrrolysine
    Polycarpo, C
    Ambrogelly, A
    Bérubé, A
    Winbush, SAM
    McCloskey, JA
    Crain, PF
    Wood, JL
    Söll, D
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (34) : 12450 - 12454
  • [9] Selenocysteine, Pyrrolysine, and the Unique Energy Metabolism of Methanogenic Archaea
    Rother, Michael
    Krzycki, Joseph A.
    [J]. ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL, 2010, 2010
  • [10] Pyrrolysine encoded by UAG in Archaea: Charging of a UAG-decoding specialized tRNA
    Srinivasan, G
    James, CM
    Krzycki, JA
    [J]. SCIENCE, 2002, 296 (5572) : 1459 - 1462