Treatment of GERD complications (Barrett's, peptic stricture) and extra-oesophageal syndromes

被引:16
作者
Bansal, Ajay [2 ,3 ]
Kahrilas, Peter J. [1 ]
机构
[1] Northwestern Univ, Div Gastroenterol, Feinberg Sch Med, Dept Med, Chicago, IL 60611 USA
[2] Vet Affairs Med Ctr, Dept Med, Kansas City, MO USA
[3] Univ Kansas, Kansas City, MO USA
关键词
Barret' s oesophagus; Oesophageal adenocarcinoma; Peptic stricture; Extra oesophageal GERD; HIGH-GRADE DYSPLASIA; PROTON PUMP INHIBITORS; GASTROESOPHAGEAL-REFLUX; RADIOFREQUENCY ABLATION; PHOTODYNAMIC THERAPY; RANDOMIZED-TRIAL; ADENOCARCINOMA; METAANALYSIS; LARYNGITIS; REGRESSION;
D O I
10.1016/j.bpg.2010.09.007
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Apart from typical reflux symptoms and oesophagitis the clinical presentation of GERD can be dominated by mucosal complications of reflux (Barrett s oesophagus oesophageal adenocarcinoma Peptic structure) or by extra-oesophageal syndromes most notably asthma laryngitis or chronic cough Managing these entities is much less straightforward than with oesophagitis With respect to adenocarcinoma metaplasia and dysplasia are recognised precursors but the potential of these lesions to evolve to cancer has not been shown to lessen as a result of treatment medical or surgical Consequently management focuses on strategies to identify and eliminate high-grade dysplasia and intra-mucosal cancer lesions that are potentially curable by endoscopic ablation or surgical resection With respect to the extra-oesophageal GERD syndromes these are increasingly recognised as multifactorial conditions with reflux as in exacerbating factor Treatment trials have been generally disappointing and the clinical challenge remains in accurately identifying afflicted patients who might benefit from more intensive medical or surgical reflux treatment Published by Elsevier Ltd
引用
收藏
页码:961 / 968
页数:8
相关论文
共 48 条
[1]   Does laparoscopic fundoplication provide long-term control of gastroesophageal reflux related cough? [J].
Allen, CJ ;
Anvari, M .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2004, 18 (04) :633-637
[2]   Argon Plasma Coagulation of Cervical Heterotopic Gastric Mucosa as an Alternative Treatment for Globus Sensations [J].
Bajbouj, Monther ;
Becker, Valentin ;
Eckel, Florian ;
Miehlke, Stephan ;
Pech, Oliver ;
Prinz, Christian ;
Schmid, Roland M. ;
Meining, Alexander .
GASTROENTEROLOGY, 2009, 137 (02) :440-444
[3]  
Caldwell MTP, 1996, GASTROENTEROLOGY, V110, pA74
[4]   Systematic review and meta-analysis of randomised controlled trials of gastro-oesophageal reflux interventions for chronic cough associated with gastro-oesophageal reflux [J].
Chang, AB ;
Lasserson, TJ ;
Kiljander, TO ;
Connor, FL ;
Gaffney, JT ;
Garske, LA .
BMJ-BRITISH MEDICAL JOURNAL, 2006, 332 (7532) :11-14
[5]   Complete Barrett's Eradication Endoscopic Mucosal Resection: An Effective Treatment Modality for High-Grade Dysplasia and Intramucosal Carcinoma-An American Single-Center Experience [J].
Chennat, Jennifer ;
Konda, Vani J. A. ;
Ross, Andrew S. ;
de Tejada, Alberto Herreros ;
Noffsinger, Amy ;
Hart, John ;
Lin, Shang ;
Ferguson, Mark K. ;
Posner, Mitchell C. ;
Waxman, Irving .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2009, 104 (11) :2684-2692
[6]   Does a surgical antireflux procedure decrease the incidence of esophageal adenocarcinoma in Barrett's esophagus? A meta-analysis [J].
Corey, KE ;
Schmitz, SM ;
Shaheen, NJ .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (11) :2390-2394
[7]   Medical treatment for reflux oesophagitis does not consistently improve asthma control: a systematic review [J].
Coughlan, JL ;
Gibson, PG ;
Henry, RL .
THORAX, 2001, 56 (03) :198-204
[8]  
CROBE JL, 1984, J CLIN GASTROENTEROL, V6, P109
[9]   Low-Grade Dysplasia in Barrett's Esophagus: Overdiagnosed and Underestimated [J].
Curvers, Wouter L. ;
ten Kate, Fiebo J. ;
Krishnadath, Kausilia K. ;
Visser, Mike ;
Elzer, Brenda ;
Baak, Lubertus C. ;
Bohmer, Clarisse ;
Mallant-Hent, Rosalie C. ;
van Oijen, Arnout ;
Naber, Anton H. ;
Scholten, Pieter ;
Busch, Olivier R. ;
Blaauwgeers, Harriet G. T. ;
Meijer, Gerrit A. ;
Bergman, Jacques J. G. H. M. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (07) :1523-1530
[10]   Effect of antisecretory therapy on atypical symptoms in gastroesophageal reflux disease [J].
Dore, Maria Pina ;
Pedroni, Antonietta ;
Pes, Gianni M. ;
Maragkoudakis, Emanouil ;
Tadeu, Vincenza ;
Pirina, Pietro ;
Realdi, Giuseppe ;
Delitala, Giuseppe ;
Malaty, Hoda M. .
DIGESTIVE DISEASES AND SCIENCES, 2007, 52 (02) :463-468