Complete elimination is a difficult goal for trachoma programs in severely affected communities

被引：16

作者：

Gill, Deborah A. ^{[1
,2
]}

Lakew, Takele ^{[4
]}

Alemayehu, Wondu ^{[4
]}

Melese, Muluken ^{[4
]}

Zhou, Zhaoxia ^{[1
]}

House, Jenafir I. ^{[1
]}

Hong, Kevin C. ^{[1
]}

Ray, Kathryn J. ^{[1
]}

Gandhi, Nandini ^{[1
]}

Whitcher, John P. ^{[1
,2
,3
,5
]}

Gaynor, Bruce D. ^{[1
,2
]}

Lietman, Thomas M. ^{[1
,2
,3
,5
]}

机构：

[1] Univ Calif San Francisco, F I Proctor Fdn, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Ophthalmol, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA

[4] Orbis Int, Addis Ababa, Ethiopia

[5] Univ Calif San Francisco, Inst Globe Hlth, San Francisco, CA 94143 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2008年 / 46卷 / 04期

关键词：

CHLAMYDIA-TRACHOMATIS; MASS TREATMENT; INFECTION;

D O I：

10.1086/526777

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The World Health Organization has distributed millions of doses of azithromycin to control the ocular chlamydial infection that causes trachoma. Theoretically, a loftier goal of elimination is feasible. Here, we demonstrate that, although local elimination of infection in the most severely affected communities is difficult, it is possible with biannual antibiotic distributions.

引用

页码：564 / 566

页数：3

共 13 条

[1] MOLECULAR EPIDEMIOLOGY OF TRACHOMA IN A GAMBIAN VILLAGE [J].

BAILEY, RL ;

HAYES, L ;

PICKETT, M ;

WHITTLE, HC ;

WARD, ME ;

MABEY, DCW .

BRITISH JOURNAL OF OPHTHALMOLOGY, 1994, 78 (11) :813-817

[2] Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community:: a longitudinal study [J].

Burton, MJ ;

Holland, MJ ;

Makalo, P ;

Aryee, EAN ;

Alexander, NDE ;

Sillah, A ;

Faal, H ;

West, SK ;

Foster, A ;

Johnson, GJ ;

Mabey, DCW ;

Bailey, RL .

LANCET, 2005, 365 (9467) :1321-1328

[3] Effect of a single mass antibiotic distribution on the prevalence of infectious trachoma [J].

Chidambaram, JD ;

Alemayehu, W ;

Melese, M ;

Lakew, T ;

Yi, E ;

House, J ;

Cevallos, V ;

Zhou, ZX ;

Maxey, K ;

Lee, DC ;

Shapiro, BL ;

Srinivasan, M ;

Porco, T ;

Whitcher, JP ;

Gaynor, BD ;

Lietman, TM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2006, 295 (10) :1142-1146

[4] Review of the evidence base for the 'F' and 'E' components of the SAFE strategy for trachoma control [J].

Emerson, PM ;

Cairncross, S ;

Bailey, RL ;

Mabey, DCW .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2000, 5 (08) :515-527

[5] Eliminating trachoma in areas with limited disease [J].

Gaynor, BD ;

Miao, YH ;

Cevallos, V ;

Jha, H ;

Chaudary, JSP ;

Bhatta, R ;

Osaki-Holm, S ;

Yi, E ;

Schachter, J ;

Whitcher, JP ;

Lietman, T .

EMERGING INFECTIOUS DISEASES, 2003, 9 (05) :596-598

[6] Seasonal effects in the elimination of trachoma [J].

Lee, DC ;

Chidambaram, JD ;

Porco, TC ;

Lietman, TM .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2005, 72 (04) :468-470

[7] Global elimination of trachoma: How frequently should we administer mass chemotherapy? [J].

Lietman, T ;

Porco, T ;

Dawson, C ;

Blower, S .

NATURE MEDICINE, 1999, 5 (05) :572-576

[8] New steps toward eliminating blinding trachoma [J].

Mariotti, SP .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (19) :2004-2007

[9] Feasibility of eliminating ocular Chlamydia trachomatis with repeat mass antibiotic treatments [J].

Melese, M ;

Chidambaram, JD ;

Alemayelm, W ;

Lee, DC ;

Yi, EH ;

Cevallos, V ;

Zhou, ZX ;

Donnellan, C ;

Saidel, M ;

Whitcher, JP ;

Gaynor, BD ;

Lietman, TM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (06) :721-725

[10] A rationale for continuing mass antibiotic distributions for trachoma [J].

Ray, Kathryn J. ;

Porco, Travis C. ;

Hong, Kevin C. ;

Lee, David C. ;

Alemayehu, Wondu ;

Melese, Muluken ;

Lakew, Takele ;

Yi, Elizabeth ;

House, Jenafir ;

Chidambaram, Jaya D. ;

Whitcher, John P. ;

Gaynor, Bruce D. ;

Lietman, Thomas M. .

BMC INFECTIOUS DISEASES, 2007, 7

← 1 2 →