Two-dimensional nuclear Overhauser effect experiment in a protein: the first NOESY (1979-80)

被引：8

作者：

Kumar, A ^{[1
]}

机构：

[1] Indian Inst Sci, Dept Phys, Bangalore, Karnataka, India

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 2003年 / 41卷

关键词：

two-dimensional NMR; NOESY; COSY; proton-proton NOE; proteins; biomolecules; secondary structure; three-dimensional structure; liquid-state NMR;

D O I：

10.1002/mrc.1237

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The development of two-dimensional proton-proton nuclear Overhauser effect spectroscopy was a seminal development in the algorithm of protein structure determination by liquid-state NMR. This article provides a historical and personal view of the various facilities, challenges and solutions in the successful development of this experiment for biomolecules in Professor Wuthrich's laboratory during the academic year 1979- 80. Copyright (C) 2003 John Wiley Sons, Ltd.

引用

页码：S26 / S32

页数：7

共 10 条

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[8] H-1-NMR STUDIES OF THE CONFORMATION OF CARDIOTOXIN VII2 FROM NAJA-MOSSAMBICA-MOSSAMBICA
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[10] Wuthrich K., 1986, NMR PROTEINS NUCL AC, DOI DOI 10.1051/EPN/19861701011

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