Management of cardiac dysfunction in neonates with pulmonary hypertension and the role of the ductus arteriosus

被引:9
作者
Ruoss, J. L. [1 ]
Moronta, S. Cavallaro [2 ]
Bazacliu, C. [1 ]
Giesinger, R. E. [2 ]
McNamara, P. J. [2 ]
机构
[1] Univ Florida, Dept Pediat, Div Neonatol, Gainesville, FL USA
[2] Univ Iowa, Dept Pediat, Div Neonatol, Iowa City, IA 52242 USA
关键词
Patent ductus arteriosus; Ventricular function; Pulmonary hypertension; Targeted neonatal echocardiography; RIGHT-VENTRICULAR FUNCTION; NEWBORN; ECHOCARDIOGRAPHY; PATHOPHYSIOLOGY; HYPERTROPHY; EPINEPHRINE; PHYSIOLOGY; DOPAMINE; GEOMETRY; FAILURE;
D O I
10.1016/j.siny.2022.101368
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Pulmonary hypertension in the neonate is associated with cardiopulmonary disturbances and neurodevelopment morbidity. The patent ductus arteriosus is a persistent fetal shunt that can be pathologic vs supportive in the setting of neonatal pulmonary hypertension. Understanding the underlying pathophysiology of pulmonary hypertension and the cardiopulmonary effects of various phenotypes can guide management in this vulnerable population. In this narrative, we will summarize the physiologic principles of pulmonary hypertension, the impact of the patent ductus arteriosus on various phenotypes, and the utility of serial targeted neonatal echocardiography to individualize clinical assessment and management.
引用
收藏
页数:10
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共 57 条
[41]   The right ventricle in pulmonary arterial hypertension [J].
Naeije, Robert ;
Manes, Alessandra .
EUROPEAN RESPIRATORY REVIEW, 2014, 23 (134) :476-487
[42]   Biomechanics of the right ventricle in health and disease [J].
Naeije, Robert ;
Brimioulle, Serge ;
Dewachter, Laurence .
PULMONARY CIRCULATION, 2014, 4 (03) :395-406
[43]   The Relationship Between the Right Ventricle and its Load in Pulmonary Hypertension [J].
Noordegraaf, Anton Vonk ;
Westerhof, Berend E. ;
Westerhof, Nico .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2017, 69 (02) :236-243
[44]   Morphologic characterization of the patent ductus arteriosus in the premature infant and the choice of transcatheter occlusion device [J].
Philip, Ranjit ;
Waller, B. Rush, III ;
Agrawal, Vijaykumar ;
Wright, Dena ;
Arevalo, Alejandro ;
Zurakowski, David ;
Sathanandam, Shyam .
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2016, 87 (02) :310-317
[45]   The right ventricle: interaction with the pulmonary circulation [J].
Pinsky, Michael R. .
CRITICAL CARE, 2016, 20
[46]   Ventricular Geometry, Strain, and Rotational Mechanics in Pulmonary Hypertension [J].
Puwanant, Sarinya ;
Park, Margaret ;
Popovic, Zoran B. ;
Tang, W. H. Wilson ;
Farha, Samar ;
George, Deepa ;
Sharp, Jacqueline ;
Puntawangkoon, Jirapa ;
Loyd, James E. ;
Erzurum, Serpil C. ;
Thomas, James D. .
CIRCULATION, 2010, 121 (02) :259-266
[47]   Hemodynamic optimization for neonates with neonatal encephalopathy caused by a hypoxic ischemic event: Physiological and therapeutic considerations [J].
Rios, Danielle R. ;
Lapointe, Anie ;
Schmolzer, Georg M. ;
Mohammad, Khorshid ;
VanMeurs, Krisa P. ;
Keller, Roberta L. ;
Sehgal, Arvind ;
Lakshminrusimha, Satyan ;
Giesinger, Regan E. .
SEMINARS IN FETAL & NEONATAL MEDICINE, 2021, 26 (04)
[48]   COMPARISON OF PRESSURE-VOLUME RELATIONS OF FETAL, NEWBORN, AND ADULT HEART [J].
ROMERO, T ;
FRIEDMAN, WF ;
COVELL, J .
AMERICAN JOURNAL OF PHYSIOLOGY, 1972, 222 (05) :1285-+
[49]   Post-interventional Evaluation and Follow-Up in Children With Patent Ductus Arteriosus Complicated With Moderate to Severe Pulmonary Arterial Hypertension: A Retrospective Study [J].
Rong, Xing ;
Ye, Qiaofang ;
Wang, Qiaoyu ;
Wang, Jiajun ;
Zhu, Qiongjun ;
Chen, Youran ;
Wu, Rongzhou .
FRONTIERS IN CARDIOVASCULAR MEDICINE, 2021, 8
[50]   Cardiac Catheterization and Hemodynamics in a Multicenter Cohort of Children with Pulmonary Hypertension [J].
Rosenzweig, Erika B. ;
Bates, Angela ;
Mullen, Mary P. ;
Abman, Steven H. ;
Austin, Eric D. ;
Everett, Allen ;
Fineman, Jeffrey ;
Feinstein, Jeffery ;
Hopper, Rachel K. ;
Kinsella, John P. ;
Krishnan, Usha S. ;
Lu, Minmin ;
Mandl, Kenneth D. ;
Raj, J. Usha ;
Varghese, Nidhy ;
Yung, Delphine ;
Handler, Stephanie S. ;
Sleeper, Lynn A. .
ANNALS OF THE AMERICAN THORACIC SOCIETY, 2022, 19 (06) :1000-1012