Fetal growth restriction associated with measles virus infection during pregnancy

被引:13
作者
Kobayashi, K [1 ]
Tajima, M
Toishi, S
Fujimori, K
Suzuki, Y
Udagawa, H
机构
[1] Asahi Gen Hosp, Dept Obstet & Gynecol, Asahi, Chiba 2852511, Japan
[2] Asahi Gen Hosp, Div Neonatol, Perinatal Ctr, Asahi, Chiba 2852511, Japan
[3] Asahi Gen Hosp, Dept Pathol, Asahi, Chiba 2852511, Japan
关键词
fetal growth; measles virus; pregnancy;
D O I
10.1515/JPM.2005.011
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
We report on a 28-week infant with growth restriction starting after 23 weeks' gestation because of measles virus (MV) infection of the mother. Histological findings for the placenta revealed extensive fibrin deposition and necrosis of the villi, and MV antigen was demonstrated in the syncytiotrophoblast by immunostaining. The MV-specific IgM level in the infant was negative, but that of the mother was positive. Therefore, we speculate that growth restriction is not attributed to direct infection with MV, but to placental dysfunction due to a decrease in intravillous blood flow and oxygen supply to the fetus.
引用
收藏
页码:67 / 68
页数:2
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