Technology for Innovation in Radiation Oncology

被引:49
作者
Chetty, Indrin J. [1 ]
Martel, Mary K. [2 ]
Jaffray, David A. [3 ,4 ]
Benedict, Stanley H. [5 ]
Hahn, Stephen M. [6 ]
Berbeco, Ross [7 ]
Deye, James [8 ]
Jeraj, Robert [9 ]
Kavanagh, Brian [10 ]
Krishnan, Sunil [6 ]
Lee, Nancy [11 ]
Low, Daniel A. [12 ]
Mankoff, David [13 ]
Marks, Lawrence B. [14 ]
Ollendorf, Daniel [15 ]
Paganetti, Harald [16 ]
Ross, Brian [17 ]
Siochi, Ramon Alfredo C. [18 ]
Timmerman, Robert D. [19 ]
Wong, John W. [20 ]
机构
[1] Henry Ford Hosp, Dept Radiat Oncol, Detroit, MI 48202 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Radiat Phys, Houston, TX 77030 USA
[3] Princess Margaret Hosp, Dept Radiat Oncol, Toronto, ON M4X 1K9, Canada
[4] Princess Margaret Hosp, Dept Med Biophys, Toronto, ON M4X 1K9, Canada
[5] Univ Calif Davis, Ctr Canc, Dept Radiat Oncol, Sacramento, CA 95817 USA
[6] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA
[7] Brigham & Womens Hosp, Dept Radiat Oncol, Boston, MA 02115 USA
[8] Natl Canc Inst, Radiat Res Programs, Bethesda, MD USA
[9] Univ Wisconsin, Dept Med Phys, Madison, WI 53706 USA
[10] Univ Colorado, Dept Radiat Oncol, Aurora, CO USA
[11] Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, New York, NY 10021 USA
[12] Univ Calif Los Angeles, Dept Radiat Oncol, Los Angeles, CA 90024 USA
[13] Univ Washington, Sch Med, Dept Radiol, Seattle, WA USA
[14] Univ North Carolina Hosp, Dept Radiat Oncol, Chapel Hill, NC USA
[15] Inst Clin & Econ Review, Boston, MA USA
[16] Proton Therapy Ctr, Dept Radiat Oncol, Massachusetts Gen Hosp, Boston, MA USA
[17] Univ Michigan Hlth Syst, Dept Radiol, Ann Arbor, MI USA
[18] W Virginia Univ, Dept Radiat Oncol, Morgantown, WV 26506 USA
[19] Univ Texas SW Med Ctr Dallas, Dept Radiat Oncol, Dallas, TX 75390 USA
[20] Johns Hopkins Univ, Dept Radiat Oncol, Baltimore, MD USA
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2015年 / 93卷 / 03期
关键词
PROTON-BEAM; GOLD NANOPARTICLES; PROSTATE-CANCER; CLINICAL-TRIALS; RADIOTHERAPY; THERAPY; FUTURE; RISK; MRI; SIMULATION;
D O I
10.1016/j.ijrobp.2015.07.007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radiation therapy is an effective, personalized cancer treatment that has benefited from technological advances associated with the growing ability to identify and target tumors with accuracy and precision. Given that these advances have played a central role in the success of radiation therapy as a major component of comprehensive cancer care, the American Society for Radiation Oncology (ASTRO), the American Association of Physicists in Medicine (AAPM), and the National Cancer Institute (NCI) sponsored a workshop entitled "Technology for Innovation in Radiation Oncology," which took place at the National Institutes of Health (NIH) in Bethesda, Maryland, on June 13 and 14, 2013. The purpose of this workshop was to discuss emerging technology for the field and to recognize areas for greater research investment. Expert clinicians and scientists discussed innovative technology in radiation oncology, in particular as to how these technologies are being developed and translated to clinical practice in the face of current and future challenges and opportunities. Technologies encompassed topics in functional imaging, treatment devices, nanotechnology, and information technology. The technical, quality, and safety performance of these technologies were also considered. A major theme of the workshop was the growing importance of innovation in the domain of process automation and oncology informatics. The technologically advanced nature of radiation therapy treatments predisposes radiation oncology research teams to take on informatics research initiatives. In addition, the discussion on technology development was balanced with a parallel conversation regarding the need for evidence of efficacy and effectiveness. The linkage between the need for evidence and the efforts in informatics research was clearly identified as synergistic. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:485 / 492
页数:8
相关论文
共 54 条
[1]   Cost Implications and Complications of Overtreatment of Low-Risk Prostate Cancer in the United States [J].
Aizer, Ayal A. ;
Gu, Xiangmei ;
Chen, Ming-Hui ;
Choueiri, Toni K. ;
Martin, Neil E. ;
Efstathiou, Jason A. ;
Hyatt, Andrew S. ;
Graham, Powell L. ;
Trinh, Quoc-Dien ;
Hu, Jim C. ;
Nguyen, Paul L. .
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2015, 13 (01) :61-68
[2]   An evidence based review of proton beam therapy: The report of ASTRO's emerging technology committee [J].
Allen, Aaron M. ;
Pawlicki, Todd ;
Dong, Lei ;
Fourkal, Eugene ;
Buyyounouski, Mark ;
Cengel, Keith ;
Plastaras, John ;
Bucci, Mary K. ;
Yock, Torunn I. ;
Bonilla, Luisa ;
Price, Robert ;
Harris, Eleanor E. ;
Konski, Andre A. .
RADIOTHERAPY AND ONCOLOGY, 2012, 103 (01) :8-11
[3]   Exploiting grid technologies for the simulation of clinical trials: the paradigm of in silico radiation oncology [J].
Athanaileas, Theodoros ;
Menychtas, Andreas ;
Dionysiou, Dimitra ;
Kyriazis, Dimosthenis ;
Kaklamani, Dimitra ;
Varvarigou, Theodora ;
Uzunoglu, Nikolaos ;
Stamatakos, Georgios .
SIMULATION-TRANSACTIONS OF THE SOCIETY FOR MODELING AND SIMULATION INTERNATIONAL, 2011, 87 (10) :893-910
[4]   Redesigning Radiotherapy Quality Assurance: Opportunities to Develop an Efficient, Evidence-Based System to Support Clinical Trials-Report of the National Cancer Institute Work Group on Radiotherapy Quality Assurance [J].
Bekelman, Justin E. ;
Deye, James A. ;
Vikram, Bhadrasain ;
Bentzen, Soren M. ;
Bruner, Deborah ;
Curran, Walter J., Jr. ;
Dignam, James ;
Efstathiou, Jason A. ;
FitzGerald, T. J. ;
Hurkmans, Coen ;
Ibbott, Geoffrey S. ;
Lee, J. Jack ;
Merchant, Thomas E. ;
Michalski, Jeff ;
Palta, Jatinder R. ;
Simon, Richard ;
Ten Haken, Randal K. ;
Timmerman, Robert ;
Tunis, Sean ;
Coleman, C. Norman ;
Purdy, James .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2012, 83 (03) :782-790
[5]   Implications of comparative effectiveness research for radiation oncology [J].
Bekelman, Justin E. ;
Shah, Anand ;
Hahn, Stephen M. .
PRACTICAL RADIATION ONCOLOGY, 2011, 1 (02) :72-80
[6]   DNA Damage Enhancement from Gold Nanoparticles for Clinical MV Photon Beams [J].
Berbeco, Ross I. ;
Korideck, Houari ;
Ngwa, Wilfred ;
Kumar, Rajiv ;
Patel, Janki ;
Sridhar, Srinivas ;
Johnson, Sarah ;
Price, Brendan D. ;
Kimmelman, Alec ;
Makrigiorgos, G. Mike .
RADIATION RESEARCH, 2012, 178 (06) :604-608
[7]   An in-silico comparison of proton beam and IMRT for postoperative radiotherapy in completely resected stage IIIA non-small cell lung cancer [J].
Berman, Abigail T. ;
Teo, Boon-Keng Kevin ;
Dolney, Derek ;
Swisher-McClure, Samuel ;
Shahnazi, Kambiz ;
Both, Stefan ;
Rengan, Ramesh .
RADIATION ONCOLOGY, 2013, 8
[8]   Spatiotemporal Stability of Cu-ATSM and FLT Positron Emission Tomography Distributions During Radiation Therapy [J].
Bradshaw, Tyler J. ;
Yip, Stephen ;
Jallow, Ngoneh ;
Forrest, Lisa J. ;
Jeraj, Robert .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2014, 89 (02) :399-405
[9]   Dose Escalation, Not "New Biology," Can Account for the Efficacy of Stereotactic Body Radiation Therapy With Non-Small Cell Lung Cancer [J].
Brown, J. Martin ;
Brenner, David J. ;
Carlson, David J. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 85 (05) :1159-1160
[10]   A Collaborative Enterprise for Multi-Stakeholder Participation in the Advancement of Quantitative Imaging [J].
Buckler, Andrew J. ;
Bresolin, Linda ;
Dunnick, N. Reed ;
Sullivan, Daniel C. .
RADIOLOGY, 2011, 258 (03) :906-914