Fibroblast growth factor 21 for non-alcoholic steatohepatitis

被引：9

作者：

Wong, Vincent W. S. ^{[1
]}

Adams, Leon A. ^{[2
]}

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut 9F, Shatin, Clin Sci Bldg, Hong Kong, Peoples R China

[2] Univ Western Australia, Perth, WA, Australia

来源：

LANCET | 2018年 / 392卷 / 10165期

关键词：

FATTY LIVER;

D O I：

10.1016/S0140-6736(18)32165-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2658 / 2660

页数：4

共 12 条

[1] Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease [J].

Estes, Chris ;

Razavi, Homie ;

Loomba, Rohit ;

Younossi, Zobair ;

Sanyal, Arun J. .

HEPATOLOGY, 2018, 67 (01) :123-133

[2] NGM282 for treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial [J].

Harrison, Stephen A. ;

Rinella, Mary E. ;

Abdelmalek, Manal F. ;

Trotter, James F. ;

Paredes, Angelo H. ;

Arnold, Hays L. ;

Kugelmas, Marcelo ;

Bashir, Mustafa R. ;

Jaros, Mark J. ;

Ling, Lei ;

Rossi, Stephen J. ;

DePaoli, Alex M. ;

Loomba, Rohit .

LANCET, 2018, 391 (10126) :1174-1185

[3] Prognostic Value of Controlled Attenuation Parameter by Transient Elastography [J].

Liu, Ken ;

Wong, Vincent Wai-Sun ;

Lau, Keith ;

Du Liu, Sienna ;

Tse, Yee-Kit ;

Yip, Terry Cheuk-Fung ;

Kwok, Raymond ;

Chan, Alex Yiu-Wa ;

Chan, Henry Lik-Yuen ;

Wong, Grace Lai-Hung .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2017, 112 (12) :1812-1823

[4] GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease [J].

Loomba, Rohit ;

Kayali, Zeid ;

Noureddin, Mazen ;

Ruane, Peter ;

Lawitz, Eric J. ;

Bennett, Michael ;

Wang, Lulu ;

Harting, Eliza ;

Tarrant, Jacqueline M. ;

McColgan, Bryan J. ;

Chung, Chuhan ;

Ray, Adrian S. ;

Subramanian, G. Mani ;

Myers, Robert P. ;

Middleton, Michael S. ;

Lai, Michelle ;

Charlton, Michael ;

Harrison, Stephen A. .

GASTROENTEROLOGY, 2018, 155 (05) :1463-+

[5] Fatty liver and FGF21 physiology [J].

Maratos-Flier, Eleftheria .

EXPERIMENTAL CELL RESEARCH, 2017, 360 (01) :2-5

[6] Association of noninvasive quantitative decline in liver fat content on MRI with histologic response in nonalcoholic steatohepatitis [J].

Patel, Janki ;

Bettencourt, Ricki ;

Cui, Jeffrey ;

Salotti, Joanie ;

Hooker, Jonathan ;

Bhatt, Archana ;

Hernandez, Carolyn ;

Phirum Nguyen ;

Aryafar, Hamed ;

Valasek, Mark ;

Haufe, William ;

Hooker, Catherine ;

Richards, Lisa ;

Sirlin, Claude B. ;

Loomba, Rohit .

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2016, 9 (05) :692-701

[7] Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial [J].

Sanyal, Arun ;

Charles, Edgar D. ;

Neuschwander-Tetri, Brent A. ;

Loomba, Rohit ;

Harrison, Stephen A. ;

Abdelmalek, Manal F. ;

Lawitz, Eric J. ;

Halegoua-DeMarzio, Dina ;

Kundu, Sudeep ;

Noviello, Stephanie ;

Luo, Yi ;

Christian, Rose .

LANCET, 2018, 392 (10165) :2705-2717

[8]

Sonoda J, 2017, HORM MOL BIOL CLIN I, V30, DOI 10.1515/hmbci-2017-0002

[9] Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis [J].

Vilar-Gomez, Eduardo ;

Martinez-Perez, Yadina ;

Calzadilla-Bertot, Luis ;

Torres-Gonzalez, Ana ;

Gra-Oramas, Bienvenido ;

Gonzalez-Fabian, Licet ;

Friedman, Scott L. ;

Diago, Moises ;

Romero-Gomez, Manuel .

GASTROENTEROLOGY, 2015, 149 (02) :367-+

[10] Noninvasive biomarkers in NAFLD and NASH - current progress and future promise [J].

Wong, Vincent Wai-Sun ;

Adams, Leon A. ;

de Ledinghen, Victor ;

Wong, Grace Lai-Hung ;

Sookoian, Silvia .

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2018, 15 (08) :461-478

← 1 2 →