Bone mineral density and joint cartilage: four clinical settings of a complex relationship in osteoarthritis

被引:45
作者
Herrero-Beaumont, Gabriel [1 ]
Roman-Blas, Jorge A. [1 ]
Largo, Raquel [1 ]
Berenbaum, Francis [2 ]
Castaneda, Santos [3 ]
机构
[1] Univ Autonoma Madrid, IIS Fdn Jimenez Diaz, Serv Rheumatol, Bone & Joint Res Unit, Madrid 28040, Spain
[2] Univ Paris 06, St Antoine Hosp, AP HP, Dept Rheumatol, Paris, France
[3] Univ Autonoma Madrid, IIS Princesa, Hosp Princesa, Dept Rheumatol, Madrid 28040, Spain
关键词
RADIOGRAPHIC KNEE OSTEOARTHRITIS; SUBCHONDRAL BONE; ARTICULAR-CARTILAGE; HAND OSTEOARTHRITIS; HIP OSTEOARTHRITIS; ELDERLY-MEN; OSTEOPOROTIC FRACTURES; INVERSE RELATIONSHIP; WOMEN; POPULATION;
D O I
10.1136/ard.2011.151233
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Experimental and clinical data support the hypothesis that both high and low bone mineral density (BMD) conditions, including osteoporosis, may induce osteoarthritis. However, these conditions do not always predispose to osteoarthritis progression. Four clinical settings could arise from this relationship, and furthermore two phenotypes may be identified whether early osteoarthritis coexists with high or low BMD.
引用
收藏
页码:1523 / 1525
页数:3
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